SEARCH

SEARCH BY CITATION

References

  • 1
    Ye, P., Rodriguez, F. H., Kanaly, S., Stocking, K. L., Schurr, J., Schwarzenberger, P., Oliver, P. et al., Requirement of interleukin 17 receptor signaling for lung CXC chemokine and granulocyte colony-stimulating factor expression, neutrophil recruitment, and host defense. J. Exp. Med. 2001. 194: 519527.
  • 2
    Mangan, P. R., Harrington, L. E., O'Quinn, D. B., Helms, W. S., Bullard, D. C., Elson, C. O., Hatton, R. D. et al., Transforming growth factor-beta induces development of the T(H)17 lineage. Nature 2006. 441: 231234.
  • 3
    Huang, W., Na, L., Fidel, P. L. and Schwarzenberger, P., Requirement of interleukin-17A for systemic anti-Candida albicans host defense in mice. J. Infect. Dis. 2004. 190: 624631.
  • 4
    Mills, K. H., Induction, function and regulation of IL-17-producing T cells. Eur. J. Immunol. 2008. 38: 26362649.
  • 5
    Bettelli, E., Korn, T., Oukka, M. and Kuchroo, V. K., Induction and effector functions of T(H)17 cells. Nature 2008. 453: 10511057.
  • 6
    Ivanov, I. I., McKenzie, B. S., Zhou, L., Tadokoro, C. E., Lepelley, A., Lafaille, J. J., Cua, D. J. and Littman, D. R., The orphan nuclear receptor RORgammat directs the differentiation program of proinflammatory IL-17+ T helper cells. Cell 2006. 126: 11211133.
  • 7
    Yang, X. O., Pappu, B. P., Nurieva, R., Akimzhanov, A., Kang, H. S., Chung, Y., Ma, L., T Helper 17 Lineage Differentiation Is Programmed by Orphan Nuclear Receptors RORalpha and RORgamma. Immunity 2008. 28: 2939.
  • 8
    Zhou, L., Ivanov, I. I., Spolski, R., Min, R., Shenderov, K., Egawa, T., Levy, D. E. et al., IL-6 programs T(H)-17 cell differentiation by promoting sequential engagement of the IL-21 and IL-23 pathways. Nat. Immunol. 2007. 8: 967974.
  • 9
    Korn, T., Bettelli, E., Gao, W., Awasthi, A., Jager, A., Strom, T. B., Oukka, M. and Kuchroo, V. K., IL-21 initiates an alternative pathway to induce proinflammatory T(H)17 cells. Nature 2007. 448: 484487.
  • 10
    Acosta-Rodriguez, E. V., Napolitani, G., Lanzavecchia, A. and Sallusto, F., Interleukins 1beta and 6 but not transforming growth factor-beta are essential for the differentiation of interleukin 17-producing human T helper cells. Nat. Immunol. 2007. 8: 942949.
  • 11
    Wilson, N. J., Boniface, K., Chan, J. R., McKenzie, B. S., Blumenschein, W. M., Mattson, J. D., Basham, B. et al., Development, cytokine profile and function of human interleukin 17-producing helper T cells. Nat. Immunol. 2007. 8: 950957.
  • 12
    Manel, N., Unutmaz, D. and Littman, D. R., The differentiation of human T(H)-17 cells requires transforming growth factor-beta and induction of the nuclear receptor RORgammat. Nat. Immunol. 2008. 9: 641649.
  • 13
    Yang, L., Anderson, D. E., Baecher-Allan, C., Hastings, W. D., Bettelli, E., Oukka, M., Kuchroo, V. K. and Hafler, D. A., IL-21 and TGF-beta are required for differentiation of human T(H)17 cells. Nature 2008. 454: 350352.
  • 14
    Volpe, E., Servant, N., Zollinger, R., Bogiatzi, S. I., Hupe, P., Barillot, E. and Soumelis, V., A critical function for transforming growth factor-beta, interleukin 23 and proinflammatory cytokines in driving and modulating human T(H)-17 responses. Nat. Immunol. 2008. 9: 650657.
  • 15
    Acosta-Rodriguez, E. V., Rivino, L., Geginat, J., Jarrossay, D., Gattorno, M., Lanzavecchia, A., Sallusto, F. and Napolitani, G., Surface phenotype and antigenic specificity of human interleukin 17-producing T helper memory cells. Nat. Immunol. 2007. 8: 639646.
  • 16
    Hirota, K., Yoshitomi, H., Hashimoto, M., Maeda, S., Teradaira, S., Sugimoto, N., Yamaguchi, T. et al., Preferential recruitment of CCR6-expressing Th17 cells to inflamed joints via CCL20 in rheumatoid arthritis and its animal model. J. Exp. Med. 2007. 204: 28032812.
  • 17
    Langrish, C. L., Chen, Y., Blumenschein, W. M., Mattson, J., Basham, B., Sedgwick, J. D., McClanahan, T. et al., IL-23 drives a pathogenic T cell population that induces autoimmune inflammation. J. Exp. Med. 2005. 201: 233240.
  • 18
    Komiyama, Y., Nakae, S., Matsuki, T., Nambu, A., Ishigame, H., Kakuta, S., Sudo, K. and Iwakura, Y., IL-17 plays an important role in the development of experimental autoimmune encephalomyelitis. J. Immunol. 2006. 177: 566573.
  • 19
    Nakae, S., Nambu, A., Sudo, K. and Iwakura, Y., Suppression of immune induction of collagen-induced arthritis in IL-17-deficient mice. J. Immunol. 2003. 171: 61736177.
  • 20
    Hofstetter, H. H., Ibrahim, S. M., Koczan, D., Kruse, N., Weishaupt, A., Toyka, K. V. and Gold, R., Therapeutic efficacy of IL-17 neutralization in murine experimental autoimmune encephalomyelitis. Cell Immunol. 2005. 237: 123130.
  • 21
    Uyttenhove, C. and Van Snick, J., Development of an anti-IL-17A auto-vaccine that prevents experimental auto-immune encephalomyelitis. Eur. J. Immunol. 2006. 36: 28682874.
  • 22
    Lubberts, E., Koenders, M. I., Oppers-Walgreen, B., van den Bersselaar, L., Coenen-de Roo, C. J., Joosten, L. A. and van den Berg, W. B., Treatment with a neutralizing anti-murine interleukin-17 antibody after the onset of collagen-induced arthritis reduces joint inflammation, cartilage destruction, and bone erosion. Arthritis Rheum. 2004. 50: 650659.
  • 23
    Lock, C., Hermans, G., Pedotti, R., Brendolan, A., Schadt, E., Garren, H., Langer-Gould, A. et al., Gene-microarray analysis of multiple sclerosis lesions yields new targets validated in autoimmune encephalomyelitis. Nat. Med. 2002. 8: 500508.
  • 24
    Tzartos, J. S., Friese, M. A., Craner, M. J., Palace, J., Newcombe, J., Esiri, M. M. and Fugger, L., Interleukin-17 production in central nervous system-infiltrating T cells and glial cells is associated with active disease in multiple sclerosis. Am. J. Pathol. 2008. 172: 146155.
  • 25
    Pene, J., Chevalier, S., Preisser, L., Venereau, E., Guilleux, M. H., Ghannam, S., Moles, J. P. et al., Chronically inflamed human tissues are infiltrated by highly differentiated Th17 lymphocytes. J. Immunol. 2008. 180: 74237430.
  • 26
    Annunziato, F., Cosmi, L., Santarlasci, V., Maggi, L., Liotta, F., Mazzinghi, B., Parente, E. et al., Phenotypic and functional features of human Th17 cells. J. Exp. Med. 2007. 204: 18491861.
  • 27
    Duerr, R. H., Taylor, K. D., Brant, S. R., Rioux, J. D., Silverberg, M. S., Daly, M. J., Steinhart, A. H. et al., A genome-wide association study identifies IL23R as an inflammatory bowel disease gene. Science 2006. 314: 14611463.
  • 28
    Fujino, S., Andoh, A., Bamba, S., Ogawa, A., Hata, K., Araki, Y., Bamba, T. and Fujiyama, Y., Increased expression of interleukin 17 in inflammatory bowel disease. Gut 2003. 52: 6570.
  • 29
    Steinman, L., A brief history of T(H)17, the first major revision in the T(H)1/T(H)2 hypothesis of T cell-mediated tissue damage. Nat. Med. 2007. 13: 139145.
  • 30
    Ferber, I. A., Brocke, S., Taylor-Edwards, C., Ridgway, W., Dinisco, C., Steinman, L., Dalton, D. and Fathman, C. G., Mice with a disrupted IFN-gamma gene are susceptible to the induction of experimental autoimmune encephalomyelitis (EAE). J. Immunol. 1996. 156: 57.
  • 31
    Rosloniec, E. F., Latham, K. and Guedez, Y. B., Paradoxical roles of IFN-gamma in models of Th1-mediated autoimmunity. Arthritis Res. 2002. 4: 333336.
  • 32
    Willenborg, D. O., Fordham, S., Bernard, C. C., Cowden, W. B. and Ramshaw, I. A., IFN-gamma plays a critical down-regulatory role in the induction and effector phase of myelin oligodendrocyte glycoprotein-induced autoimmune encephalomyelitis. J. Immunol. 1996. 157: 32233227.
  • 33
    Panitch, H. S., Hirsch, R. L., Schindler, J. and Johnson, K. P., Treatment of multiple sclerosis with gamma interferon: exacerbations associated with activation of the immune system. Neurology 1987. 37: 10971102.
  • 34
    Chu, C. Q., Swart, D., Alcorn, D., Tocker, J. and Elkon, K. B., Interferon-gamma regulates susceptibility to collagen-induced arthritis through suppression of interleukin-17. Arthritis Rheum. 2007. 56: 11451151.
  • 35
    Raza, K., Falciani, F., Curnow, S. J., Ross, E. J., Lee, C. Y., Akbar, A. N., Lord, J. M. et al., Early rheumatoid arthritis is characterized by a distinct and transient synovial fluid cytokine profile of T cell and stromal cell origin. Arthritis Res. Ther. 2005. 7: R784R795.
  • 36
    Yamada, H., Nakashima, Y., Okazaki, K., Mawatari, T., Fukushi, J. I., Kaibara, N., Hori, A. et al., Th1 but not Th17 cells predominate in the joints of patients with rheumatoid arthritis. Ann. Rheum. Dis. 2007. 67: 12991304.
  • 37
    Firestein, G. S., Evolving concepts of rheumatoid arthritis. Nature 2003. 423: 356361.
  • 38
    Kotake, S., Udagawa, N., Takahashi, N., Matsuzaki, K., Itoh, K., Ishiyama, S., Saito, S. et al., IL-17 in synovial fluids from patients with rheumatoid arthritis is a potent stimulator of osteoclastogenesis. J. Clin. Invest. 1999. 103: 13451352.
  • 39
    Ziolkowska, M., Koc, A., Luszczykiewicz, G., Ksiezopolska-Pietrzak, K., Klimczak, E., Chwalinska-Sadowska, H. and Maslinski, W., High levels of IL-17 in rheumatoid arthritis patients: IL-15 triggers in vitro IL-17 production via cyclosporin A-sensitive mechanism. J. Immunol. 2000. 164: 28322838.
  • 40
    Liu, H. and Rohowsky-Kochan, C., Regulation of IL-17 in human CCR6+ effector memory T cells. J. Immunol. 2008. 180: 79487957.
  • 41
    Gorelik, L., Constant, S. and Flavell, R. A., Mechanism of transforming growth factor beta-induced inhibition of T helper type 1 differentiation. J. Exp. Med. 2002. 195: 14991505.
  • 42
    Feldmann, M., Development of anti-TNF therapy for rheumatoid arthritis. Nat. Rev. Immunol. 2002. 2: 364371.
  • 43
    Hinz, B., Renner, B. and Brune, K., Drug insight: cyclo-oxygenase-2 inhibitors--a critical appraisal. Nat. Clin. Pract. Rheumatol. 2007. 3: 552560.
  • 44
    Baslund, B., Tvede, N., Danneskiold-Samsoe, B., Larsson, P., Panayi, G., Petersen, J., Petersen, L. J. et al., Targeting interleukin-15 in patients with rheumatoid arthritis: a proof-of-concept study. Arthritis Rheum. 2005. 52: 26862692.
  • 45
    Sheibanie, A. F., Tadmori, I., Jing, H., Vassiliou, E. and Ganea, D., Prostaglandin E2 induces IL-23 production in bone marrow-derived dendritic cells. FASEB J. 2004. 18: 13181320.
  • 46
    Weaver, C. T., Hatton, R. D., Mangan, P. R. and Harrington, L. E., IL-17 family cytokines and the expanding diversity of effector T cell lineages. Annu. Rev. Immunol. 2007. 25: 821852.
  • 47
    Szabo, S. J., Kim, S. T., Costa, G. L., Zhang, X., Fathman, C. G. and Glimcher, L. H., A novel transcription factor, T-bet, directs Th1 lineage commitment. Cell 2000. 100: 655669.
  • 48
    Ichiyama, K., Yoshida, H., Wakabayashi, Y., Chinen, T., Saeki, K., Nakaya, M., Takaesu, G. et al., Foxp3 inhibits RORgammat-mediated IL-17A mRNA transcription through direct interaction with RORgammat. J. Biol. Chem. 2008. 283: 1700317008.
  • 49
    Boyman, O., Purton, J. F., Surh, C. D. and Sprent, J., Cytokines and T-cell homeostasis. Curr. Opin. Immunol. 2007. 19: 320326.
  • 50
    Narumiya, S., Sugimoto, Y. and Ushikubi, F., Prostanoid receptors: structures, properties, and functions. Physiol. Rev. 1999. 79: 11931226.
  • 51
    Sugimoto, Y., Narumiya, S. and Ichikawa, A., Distribution and function of prostanoid receptors: studies from knockout mice. Prog. Lipid Res. 2000. 39: 289314.
  • 52
    Jacobs, L. D., Cookfair, D. L., Rudick, R. A., Herndon, R. M., Richert, J. R., Salazar, A. M., Fischer, J. S. et al., Intramuscular interferon beta-1a for disease progression in relapsing multiple sclerosis. The Multiple Sclerosis Collaborative Research Group (MSCRG). Ann. Neurol. 1996. 39: 285294.
  • 53
    Honda, T., Segi-Nishida, E., Miyachi, Y. and Narumiya, S., Prostacyclin-IP signaling and prostaglandin E2-EP2/EP4 signaling both mediate joint inflammation in mouse collagen-induced arthritis. J. Exp. Med. 2006. 203: 325335.
  • 54
    Chizzolini, C., Chicheportiche, R., Alvarez, M., de Rham, C., Roux-Lombard, P., Ferrari-Lacraz, S. and Dayer, J. M., Prostaglandin E2 (PGE2) synergistically with interleukin-23 (IL-23) favors human Th17 expansion. Blood 2008. 112: 36963703
  • 55
    Malfait, A. M., Williams, R. O., Malik, A. S., Maini, R. N. and Feldmann, M., Chronic relapsing homologous collagen-induced arthritis in DBA/1 mice as a model for testing disease-modifying and remission-inducing therapies. Arthritis Rheum. 2001. 44: 12151224.
  • 56
    Zheng, Y., Danilenko, D. M., Valdez, P., Kasman, I., Eastham-Anderson, J., Wu, J. and Ouyang, W., Interleukin-22, a T(H)17 cytokine, mediates IL-23-induced dermal inflammation and acanthosis. Nature 2007. 445: 648651.
  • 57
    Nash, P. and Clegg, D. O., Psoriatic arthritis therapy: NSAIDs and traditional DMARDs. Ann. Rheum. Dis. 2005. 64: ii74ii77.
  • 58
    Khayrullina, T., Yen, J. H., Jing, H. and Ganea, D., In vitro differentiation of dendritic cells in the presence of prostaglandin E2 alters the IL-12/IL-23 balance and promotes differentiation of Th17 cells. J. Immunol. 2008. 181: 721735.
  • 59
    Sheibanie, A. F., Khayrullina, T., Safadi, F. F. and Ganea, D., Prostaglandin E2 exacerbates collagen-induced arthritis in mice through the inflammatory interleukin-23/interleukin-17 axis. Arthritis Rheum. 2007. 56: 26082619.
  • 60
    Harris, S. G., Padilla, J., Koumas, L., Ray, D. and Phipps, R. P., Prostaglandins as modulators of immunity. Trends Immunol. 2002. 23: 144150.
  • 61
    Benveniste, E. N. and Qin, H., Type I interferons as anti-inflammatory mediators. Sci STKE. 2007. 2007: pe70.
  • 62
    Prinz, M., Schmidt, H., Mildner, A., Knobeloch, K. P., Hanisch, U. K., Raasch, J., Merkler, D. et al., Distinct and nonredundant in vivo functions of IFNAR on myeloid cells limit autoimmunity in the central nervous system. Immunity 2008. 28: 675686.
  • 63
    Kroenke, M. A., Carlson, T. J., Andjelkovic, A. V. and Segal, B. M., IL-12- and IL-23-modulated T cells induce distinct types of EAE based on histology, CNS chemokine profile, and response to cytokine inhibition. J. Exp. Med. 2008. 205: 15351541.
  • 64
    Geginat, J., Sallusto, F. and Lanzavecchia, A., Cytokine-driven proliferation and differentiation of human naive, central memory, and effector memory CD4(+) T cells. J. Exp. Med. 2001. 194: 17111719.
  • 65
    Messi, M., Giacchetto, I., Nagata, K., Lanzavecchia, A., Natoli, G. and Sallusto, F., Memory and flexibility of cytokine gene expression as separable properties of human T(H)1 and T(H)2 lymphocytes. Nat. Immunol. 2003. 4: 7886.