SEARCH

SEARCH BY CITATION

References

  • 1
    Abraham, R. T. and Weiss, A., Jurkat T cells and development of the T-cell receptor signalling paradigm. Nat. Rev. Immunol. 2004. 4: 301308.
  • 2
    Cantrell, D. A., Transgenic analysis of thymocyte signal transduction. Nat. Rev. Immunol. 2002. 2: 2027.
  • 3
    Jordan, M. S., Singer, A. L. and Koretzky, G. A., Adaptors as central mediators of signal transduction in immune cells. Nat. Immunol. 2003. 4: 110116.
  • 4
    Zhang, W., Trible, R. P., Zhu, M., Liu, S. K., McGlade, C. J. and Samelson, L. E., Association of Grb2, Gads, and phospholipase C-gamma 1 with phosphorylated LAT tyrosine residues. Effect of LAT tyrosine mutations on T cell angigen receptor-mediated signaling. J. Biol. Chem. 2000. 275: 2335523361.
  • 5
    Irvin, B. J., Williams, B. L., Nilson, A. E., Maynor, H. O. and Abraham, R. T., Pleiotropic contributions of phospholipase C-gamma1 (PLC-gamma1) to T-cell antigen receptor-mediated signaling: reconstitution studies of a PLC-gamma1-deficient Jurkat T-cell line. Mol. Cell. Biol. 2000. 20: 91499161.
  • 6
    Yablonski, D., Kuhne, M. R., Kadlecek, T. and Weiss, A., Uncoupling of nonreceptor tyrosine kinases from PLC-gamma1 in an SLP-76-deficient T cell. Science 1998. 281: 413416.
  • 7
    Finco, T. S., Kadlecek, T., Zhang, W., Samelson, L. E. and Weiss, A., LAT is required for TCR-mediated activation of PLCgamma1 and the Ras pathway. Immunity 1998. 9: 617626.
  • 8
    Abraham, R. T., Mutant T cell lines as model systems for the dissection of T cell antigen receptor signaling pathways. Immunol. Res. 2000. 22: 95117.
  • 9
    Clements, J. L., Yang, B., Ross-Barta, S. E., Eliason, S. L., Hrstka, R. F., Williamson, R. A. and Koretzky, G. A., Requirement for the leukocyte-specific adapter protein SLP-76 for normal T cell development. Science 1998. 281: 416419.
  • 10
    Kikuchi, K., Kawasaki, Y., Ishii, N., Sasaki, Y., Asao, H., Takeshita, T., Miyoshi, I. et al., Suppression of thymic development by the dominant-negative form of Gads. Int. Immunol. 2001. 13: 777783.
  • 11
    Pivniouk, V., Tsitsikov, E., Swinton, P., Rathbun, G., Alt, F. W. and Geha, R. S., Impaired viability and profound block in thymocyte development in mice lacking the adaptor protein SLP-76. Cell 1998. 94: 229238.
  • 12
    Zhang, W., Sommers, C. L., Burshtyn, D. N., Stebbins, C. C., DeJarnette, J. B., Trible, R. P., Grinberg, A. et al., Essential role of LAT in T cell development. Immunity 1999. 10: 323332.
  • 13
    Jordan, M. S., Smith, J. E., Burns, J. C., Austin, J. E., Nichols, K. E., Aschenbrenner, A. C. and Koretzky, G. A., Complementation in trans of altered thymocyte development in mice expressing mutant forms of the adaptor molecule SLP76. Immunity 2008. 28: 359369.
  • 14
    Kumar, L., Pivniouk, V., de la Fuente, M. A., Laouini, D. and Geha, R. S., Differential role of SLP-76 domains in T cell development and function. Proc. Natl. Acad. Sci. USA 2002. 99: 884889.
  • 15
    Myung, P. S., Derimanov, G. S., Jordan, M. S., Punt, J. A., Liu, Q. H., Judd, B. A., Meyers, E. E. et al., Differential requirement for SLP-76 domains in T cell development and function. Immunity 2001. 15: 10111026.
  • 16
    Maltzman, J. S., Kovoor, L., Clements, J. L. and Koretzky, G. A., Conditional deletion reveals a cell-autonomous requirement of SLP-76 for thymocyte selection. J. Exp. Med. 2005. 202: 893900.
  • 17
    Bushar, N. D., Corbo, E., Schmidt, M., Maltzman, J. S. and Farber, D. L., Ablation of SLP-76 signaling after T cell priming generates memory CD4 T cells impaired in steady-state and cytokine-driven homeostasis. Proc. Natl. Acad. Sci. USA 2010. 107: 827831.
  • 18
    Smith-Garvin, J. E., Burns, J. C., Gohil, M., Zou, T., Kim, J. S., Maltzman, J. S., Wherry, E. J. et al., T-cell receptor signals direct the composition and function of the memory CD8+ T-cell pool. Blood 2010. 116: 55485559.
  • 19
    Wiehagen, K. R., Corbo, E., Schmidt, M., Shin, H., Wherry, E. J. and Maltzman, J. S., Loss of tonic T-cell receptor signals alters the generation but not the persistence of CD8+ memory T cells. Blood 2010. 116: 55605570.
  • 20
    Srinivas, S., Watanabe, T., Lin, C. S., William, C. M., Tanabe, Y., Jessell, T. M. and Costantini, F., Cre reporter strains produced by targeted insertion of EYFP and ECFP into the ROSA26 locus. BMC Dev. Biol. 2001. 1: 4.
  • 21
    Ruzankina, Y., Pinzon-Guzman, C., Asare, A., Ong, T., Pontano, L., Cotsarelis, G., Zediak, V. P. et al., Deletion of the developmentally essential gene ATR in adult mice leads to age-related phenotypes and stem cell loss. Cell Stem Cell 2007. 1: 113126.
  • 22
    Feil, R., Wagner, J., Metzger, D. and Chambon, P., Regulation of Cre recombinase activity by mutated estrogen receptor ligand-binding domains. Biochem. Biophys. Res. Commun. 1997. 237: 752757.
  • 23
    Abtahian, F., Guerriero, A., Sebzda, E., Lu, M. M., Zhou, R., Mocsai, A., Myers, E. E. et al., Regulation of blood and lymphatic vascular separation by signaling proteins SLP-76 and Syk. Science 2003. 299: 247251.
  • 24
    Goldrath, A. W., Sivakumar, P. V., Glaccum, M., Kennedy, M. K., Bevan, M. J., Benoist, C., Mathis, D. et al., Cytokine requirements for acute and Basal homeostatic proliferation of naive and memory CD8+ T cells. J. Exp. Med. 2002. 195: 15151522.
  • 25
    Purton, J. F., Tan, J. T., Rubinstein, M. P., Kim, D. M., Sprent, J. and Surh, C. D., Antiviral CD4+ memory T cells are IL-15 dependent. J. Exp. Med. 2007. 204: 951961.
  • 26
    Racke, M. K., Experimental autoimmune encephalomyelitis (EAE). Curr. Protoc. Neurosci. 2001. Chapter 9: Unit 9 7.
  • 27
    Hilliard, B., Samoilova, E. B., Liu, T. S., Rostami, A. and Chen, Y., Experimental autoimmune encephalomyelitis in NF-kappa B-deficient mice:roles of NF-kappa B in the activation and differentiation of autoreactive T cells. J. Immunol. 1999. 163: 29372943.
  • 28
    Jordan, M. S., Sadler, J., Austin, J. E., Finkelstein, L. D., Singer, A. L., Schwartzberg, P. L. and Koretzky, G. A., Functional hierarchy of the N-terminal tyrosines of SLP-76. J. Immunol. 2006. 176: 24302438.
  • 29
    Yablonski, D., Kadlecek, T. and Weiss, A., Identification of a phospholipase C-gamma1 (PLC-gamma1) SH3 domain-binding site in SLP-76 required for T-cell receptor-mediated activation of PLC-gamma1 and NFAT. Mol. Cell. Biol. 2001. 21: 42084218.
  • 30
    Aguado, E., Richelme, S., Nunez-Cruz, S., Miazek, A., Mura, A. M., Richelme, M., Guo, X. J. et al., Induction of T helper type 2 immunity by a point mutation in the LAT adaptor. Science 2002. 296: 20362040.
  • 31
    Sommers, C. L., Park, C. S., Lee, J., Feng, C., Fuller, C. L., Grinberg, A., Hildebrand, J. A. et al., A LAT mutation that inhibits T cell development yet induces lymphoproliferation. Science 2002. 296: 20402043.
  • 32
    Seddon, B., Legname, G., Tomlinson, P. and Zamoyska, R., Long-term survival but impaired homeostatic proliferation of naive T cells in the absence of p56lck. Science 2000. 290: 127131.
  • 33
    Seddon, B. and Zamoyska, R., TCR signals mediated by Src family kinases are essential for the survival of naive T cells. J. Immunol. 2002. 169: 29973005.
  • 34
    Steinman, L. and Zamvil, S. S., Virtues and pitfalls of EAE for the development of therapies for multiple sclerosis. Trends Immunol. 2005. 26: 565571.
  • 35
    Reboldi, A., Coisne, C., Baumjohann,D., Benvenuto, F., Bottinelli, D., Lira, S., Uccelli, A. et al., C-C chemokine receptor 6-regulated entry of TH-17 cells into the CNS through the choroid plexus is required for the initiation of EAE. Nat. Immunol. 2009. 10: 514523.
  • 36
    Waldor, M. K., Sriram, S., Hardy, R., Herzenberg, L. A., Herzenberg, L. A., Lanier, L., Lim, M. et al., Reversal of experimental allergic encephalomyelitis with monoclonal antibody to a T-cell subset marker. Science 1985. 227: 415417.
  • 37
    Shui, J. W., Boomer, J. S., Han, J., Xu, J., Dement, G. A., Zhou, G. and Tan, T. H., Hematopoietic progenitor kinase 1 negatively regulates T cell receptor signaling and T cell-mediated immune responses. Nat. Immunol. 2007. 8: 8491.
  • 38
    Carpino, N., Turner, S., Mekala, D., Takahashi, Y., Zang, H., Geiger, T. L., Doherty, P. et al., Regulation of ZAP-70 activation and TCR signaling by two related proteins, Sts-1 and Sts-2. Immunity 2004. 20: 3746.
  • 39
    Kremer, K. N., Humphreys, T. D., Kumar, A., Qian, N. X. and Hedin, K. E., Distinct role of ZAP-70 and Src homology 2 domain-containing leukocyte protein of 76 kDa in the prolonged activation of extracellular signal-regulated protein kinase by the stromal cell-derived factor-1 alpha/CXCL12 chemokine. J. Immunol. 2003. 171: 360367.
  • 40
    Baker, R. G., Hsu, C. J., Lee, D., Jordan, M. S., Maltzman, J. S., Hammer, D. A., Baumgart, T. et al., The adapter protein SLP-76 mediates “outside-in” integrin signaling and function in T cells. Mol. Cell. Biol. 2009. 29: 55785589.
  • 41
    Luckashenak, N. A., Ryszkiewicz, R. L., Ramsey, K. D. and Clements, J. L., The Src homology 2 domain-containing leukocyte protein of 76-kDa adaptor links integrin ligation with p44/42 MAPK phosphorylation and podosome distribution in murine dendritic cells. J. Immunol. 2006. 177: 51775185.
  • 42
    Mingueneau, M., Roncagalli, R., Gregoire, C., Kissenpfennig, A., Miazek, A., Archambaud, C., Wang, Y. et al., Loss of the LAT adaptor converts antigen-responsive T cells into pathogenic effectors that function independently of the T cell receptor. Immunity 2009. 31: 197208.
  • 43
    Clemens, R. A., Lenox, L. E., Kambayashi, T., Bezman, N., Maltzman, J. S., Nichols, K. E. and Koretzky, G. A., Loss of SLP-76 expression within myeloid cells confers resistance to neutrophil-mediated tissue damage while maintaining effective bacterial killing. J. Immunol. 2007. 178: 46064614.
  • 44
    O'Gorman, S., Dagenais, N. A., Qian, M. and Marchuk, Y., Protamine-Cre recombinase transgenes efficiently recombine target sequences in the male germ line of mice, but not in embryonic stem cells. Proc. Natl. Acad. Sci. USA 1997. 94: 1460214607.
  • 45
    Wu, G. F., Dandekar, A. A., Pewe, L. and Perlman, S., CD4 and CD8 T cells have redundant but not identical roles in virus-induced demyelination. J. Immunol. 2000. 165: 22782286.