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  • 1
    Zajac, A. J., Blattman, J. N., Murali-Krishna, K., Sourdive, D. J., Suresh, M., Altman, J. D. and Ahmed, R., Viral immune evasion due to persistence of activated T cells without effector function. J. Exp. Med. 1998. 188: 22052213.
  • 2
    Wherry, E. J., Blattman, J. N., Murali-Krishna, K., van der Most, R. and Ahmed, R., Viral persistence alters CD8 T-cell immunodominance and tissue distribution and results in distinct stages of functional impairment. J. Virol. 2003. 77: 49114927.
  • 3
    Moskophidis, D., Lechner, F., Pircher, H. and Zinkernagel, R. M., Virus persistence in acutely infected immunocompetent mice by exhaustion of antiviral cytotoxic effector T cells. Nature 1993. 362: 758761.
  • 4
    Agnellini, P., Wolint, P., Rehr, M., Cahenzli, J., Karrer, U. and Oxenius, A., Impaired NFAT nuclear translocation results in split exhaustion of virus-specific CD8+ T cell functions during chronic viral infection. Proc. Natl. Acad. Sci. USA 2007. 104: 45654570.
  • 5
    Virgin, H. W., Wherry, E. J. and Ahmed, R., Redefining chronic viral infection. Cell 2009. 138: 3050.
  • 6
    Karrer, U., Sierro, S., Wagner, M., Oxenius, A., Hengel, H., Koszinowski, U. H., Phillips, R. E. and Klenerman, P., Memory inflation: continuous accumulation of antiviral CD8+ T cells over time. J. Immunol. 2003. 170: 20222029.
  • 7
    Munks, M. W., Cho, K. S., Pinto, A. K., Sierro, S., Klenerman, P. and Hill, A. B., Four distinct patterns of memory CD8 T cell responses to chronic murine cytomegalovirus infection. J. Immunol. 2006. 177: 450458.
  • 8
    Karrer, U., Wagner, M., Sierro, S., Oxenius, A., Hengel, H., Dumrese, T., Freigang, S. et al., Expansion of protective CD8+ T-cell responses driven by recombinant cytomegaloviruses. J. Virol. 2004. 78: 22552264.
  • 9
    Sierro, S., Rothkopf, R. and Klenerman, P., Evolution of diverse antiviral CD8+ T cell populations after murine cytomegalovirus infection. Eur. J. Immunol. 2005. 35: 11131123.
  • 10
    Wiesel, M., Walton, S., Richter, K. and Oxenius, A., Virus-specific CD8 T cells: activation, differentiation and memory formation. Acta Pathol. Microbiol. Immunol. Scand. 2009. 117: 356381.
  • 11
    Kaech, S. M. and Wherry, E. J., Heterogeneity and cell-fate decisions in effector and memory CD8+ T cell differentiation during viral infection. Immunity 2007. 27: 393405.
  • 12
    Snyder, C. M., Cho, K. S., Bonnett, E. L., van Dommelen, S., Shellam, G. R. and Hill, A. B., Memory inflation during chronic viral infection is maintained by continuous production of short-lived, functional T cells. Immunity 2008. 29: 650659.
  • 13
    Sallusto, F., Geginat, J. and Lanzavecchia, A., Central memory and effector memory T cell subsets: function, generation, and maintenance. Annu. Rev. Immunol. 2004. 22: 745763.
  • 14
    Harty, J. T. and Badovinac, V. P., Shaping and reshaping CD8+ T-cell memory. Nat. Rev. Immunol. 2008. 8: 107119.
  • 15
    Jonjic, S., Mutter, W., Weiland, F., Reddehase, M. J. and Koszinowski, U. H., Site-restricted persistent cytomegalovirus infection after selective long-term depletion of CD4+ T lymphocytes. J. Exp. Med. 1989. 169: 11991212.
  • 16
    Arase, H., Mocarski, E. S., Campbell, A. E., Hill, A. B. and Lanier, L. L., Direct recognition of cytomegalovirus by activating and inhibitory NK cell receptors. Science 2002. 296: 13231326.
  • 17
    Snyder, C. M., Loewendorf, A., Bonnett, E. L., Croft, M., Benedict, C. A. and Hill, A. B., CD4+ T cell help has an epitope-dependent impact on CD8+ T cell memory inflation during murine cytomegalovirus infection. J. Immunol. 2009. 183: 39323941.
  • 18
    Sun, J. C. and Bevan, M. J., Defective CD8 T cell memory following acute infection without CD4 T cell help. Science 2003. 300: 339342.
  • 19
    Shedlock, D. J. and Shen, H., Requirement for CD4 T cell help in generating functional CD8 T cell memory. Science 2003. 300: 337339.
  • 20
    Vezys, V., Masopust, D., Kemball, C. C., Barber, D. L., O'Mara, L. A., Larsen, C. P., Pearson, T. C. et al., Continuous recruitment of naive T cells contributes to heterogeneity of antiviral CD8 T cells during persistent infection. J. Exp. Med. 2006. 203: 22632269.
  • 21
    Elsaesser, H., Sauer, K. and Brooks, D. G., IL-21 is required to control chronic viral infection. Science 2009. 324: 15691572.
  • 22
    Frohlich, A., Kisielow, J., Schmitz, I., Freigang, S., Shamshiev, A. T., Weber, J., Marsland, B. J. et al., IL-21R on T cells is critical for sustained functionality and control of chronic viral infection. Science 2009. 324: 15761580.
  • 23
    Yi, J. S., Du, M. and Zajac, A. J., A vital role for interleukin-21 in the control of a chronic viral infection. Science 2009. 324: 15721576.
  • 24
    Bachmann, M. F., Wolint, P., Walton, S., Schwarz, K. and Oxenius, A., Differential role of IL-2R signaling for CD8+ T cell responses in acute and chronic viral infections. Eur. J. Immunol. 2007. 37: 15021512.
  • 25
    Williams, M. A., Tyznik, A. J. and Bevan, M. J., Interleukin-2 signals during priming are required for secondary expansion of CD8+ memory T cells. Nature 2006. 441: 890893.
  • 26
    Wilson, E. B. and Livingstone, A. M., Cutting edge: CD4+ T cell-derived IL-2 is essential for help-dependent primary CD8+ T cell responses. J. Immunol. 2008. 181: 74457448.
  • 27
    Iannello, A., Boulassel, M. R., Samarani, S., Debbeche, O., Tremblay, C., Toma, E., Routy, J. P. and Ahmad, A., Dynamics and consequences of IL-21 production in HIV-infected individuals: a longitudinal and cross-sectional study. J. Immunol. 2010. 184: 114126.
  • 28
    Yue, F. Y., Lo, C., Sakhdari, A., Lee, E. Y., Kovacs, C. M., Benko, E., Liu, J. et al., HIV-specific IL-21 producing CD4(+) T cells are induced in acute and chronic progressive HIV infection and are associated with relative viral control. J. Immunol. 2010. 185: 498506.
  • 29
    Miller, N. E., Bonczyk, J. R., Nakayama, Y. and Suresh, M., Role of thymic output in regulating CD8 T-cell homeostasis during acute and chronic viral infection. J. Virol. 2005. 79: 94199429.
  • 30
    Walton, S. M., Wyrsch, P., Munks, M. W., Zimmermann, A., Hengel, H., Hill, A. B. and Oxenius, A., The dynamics of mouse cytomegalovirus-specific CD4 T cell responses during acute and latent infection. J. Immunol. 2008. 181: 11281134.
  • 31
    Buller, R. M., Holmes, K. L., Hugin, A., Frederickson, T. N. and Morse, H. C., 3rd, Induction of cytotoxic T-cell responses in vivo in the absence of CD4 helper cells. Nature 1987. 328: 7779.
  • 32
    Rahemtulla, A., Fung-Leung, W. P., Schilham, M. W., Kundig, T. M., Sambhara, S. R., Narendran, A., Arabian, A. et al., Normal development and function of CD8+ cells but markedly decreased helper cell activity in mice lacking CD4. Nature 1991. 353: 180184.
  • 33
    Janssen, E. M., Lemmens, E. E., Wolfe, T., Christen, U., von Herrath, M. G. and Schoenberger, S. P., CD4+ T cells are required for secondary expansion and memory in CD8+ T lymphocytes. Nature 2003. 421: 852856.
  • 34
    Reddehase, M. J., Podlech, J. and Grzimek, N. K., Mouse models of cytomegalovirus latency: overview. J. Clin. Virol. 2002. 25: S23S36.
  • 35
    Holtappels, R., Pahl-Seibert, M. F., Thomas, D. and Reddehase, M. J., Enrichment of immediate-early 1 (m123/pp89) peptide-specific CD8 T cells in a pulmonary CD62L(lo) memory-effector cell pool during latent murine cytomegalovirus infection of the lungs. J. Virol. 2000. 74: 1149511503.
  • 36
    Simon, C. O., Holtappels, R., Tervo, H. M., Bohm, V., Daubner, T., Oehrlein-Karpi, S. A., Kuhnapfel, B. et al., CD8 T cells control cytomegalovirus latency by epitope-specific sensing of transcriptional reactivation. J. Virol. 2006. 80: 1043610456.
  • 37
    Reddehase, M. J., Simon, C. O., Seckert, C. K., Lemmermann, N. and Grzimek, N. K., Murine model of cytomegalovirus latency and reactivation. Curr. Top. Microbiol. Immunol. 2008. 325: 315331.
  • 38
    Humphreys, I. R., Lee, S. W., Jones, M., Loewendorf, A., Gostick, E., Price, D. A., Benedict, C. A. et al., Biphasic role of 4-1BB in the regulation of mouse cytomegalovirus-specific CD8(+) T cells. Eur. J. Immunol. 2010. 40: 27622768.
  • 39
    Cook, C. H., Chen, L., Wen, J., Zimmerman, P., Zhang, Y., Trgovcich, J., Liu, Y. and Gao, J. X., CD28/B7-mediated co-stimulation is critical for early control of murine cytomegalovirus infection. Viral Immunol. 2009. 22: 91103.
  • 40
    Kontgen, F., Suss, G., Stewart, C., Steinmetz, M. and Bluethmann, H., Targeted disruption of the MHC class II Aa gene in C57BL/6 mice. Int. Immunol. 1993. 5: 957964.
  • 41
    Cobbold, S. P., Jayasuriya, A., Nash, A., Prospero, T. D. and Waldmann, H., Therapy with monoclonal antibodies by elimination of T-cell subsets in vivo. Nature 1984. 312: 548551.
  • 42
    Brune, W., Hengel, H. and Koszinowski, U. H., A mouse model for cytomegalovirus infection. Current Protocols in Immunology 2001, chapter 19: unit 19.7.
  • 43
    Altman, J. D., Moss, P. A., Goulder, P. J., Barouch, D. H., McHeyzer-Williams, M. G., Bell, J. I., McMichael, A. J. and Davis, M. M., Phenotypic analysis of antigen-specific T lymphocytes. Science 1996. 274: 9496.
  • 44
    Joller, N., Sporri, R., Hilbi, H. and Oxenius, A., Induction and protective role of antibodies in Legionella pneumophila infection. Eur. J. Immunol. 2007. 37: 34143423.