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Figure S1. The majority of IL-21 in lyn-/- spleens is expressed by CD4+ T cells.

Figure S2. IL-21-deficiency does not affect total Ig levels in lyn-/- mice.

Figure S3. Expression of PD-1 and PSGL-1 on lyn-/- and lyn-/-IL-21-/- T cells.

Figure S4. Representative FACS plots of T cells from aged mice.

Figure S5. Variability in total splenocyte numbers in aged lyn-/- mice.

Figure S6. Analyisis of kidney damage and inflammation in lyn-/-IL-21-/- mice.

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