These authors contributed equally to this work.
Foxp3-independent loss of regulatory CD4+ T-cell suppressive capacities induced by self-deprivation
Article first published online: 26 APR 2012
© 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
European Journal of Immunology
Volume 42, Issue 5, pages 1237–1249, May 2012
How to Cite
Delpoux, A., Poitrasson-Rivière, M., Le Campion, A., Pommier, A., Yakonowsky, P., Jacques, S., Letourneur, F., Randriamampita, C., Lucas, B. and Auffray, C. (2012), Foxp3-independent loss of regulatory CD4+ T-cell suppressive capacities induced by self-deprivation. Eur. J. Immunol., 42: 1237–1249. doi: 10.1002/eji.201142148
- Issue published online: 26 APR 2012
- Article first published online: 26 APR 2012
- Manuscript Accepted: 13 JAN 2012
- Manuscript Revised: 16 DEC 2011
- Manuscript Received: 4 OCT 2011
- Ligue contre le Cancer
- Ph.D. fellowship
Disclaimer: Supplementary materials have been peer-reviewed but not copyedited.
Figure 1. Highly purified self-deprived Treg cells are not functional in vitro.
Figure 2. Unaltered survival of self-deprived Treg cells in culture.
Figure 3. Interleukin (IL)-2 is not sufficient to restore the suppressive function of self-deprived Treg cells.
Figure 4. Phenotypic analysis of self-deprived Treg cells.
Figure 5. Self-deprived Treg cells from MHC IIΔ/Δ-CD3KO chimeras exhibit altered transcriptional signature.
Table 1. Primers
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