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References

  • 1
    Borregaard, N., Neutrophils, from marrow to microbes. Immunity 2010. 33: 657670.
  • 2
    Kjeldsen, L., Bainton, D. F., Sengelov, H. and Borregaard, N., Identification of neutrophil gelatinase-associated lipocalin as a novel matrix protein of specific granules in human neutrophils. Blood 1994. 83: 799807.
  • 3
    Kjeldsen, L., Johnsen, A. H., Sengelov, H. and Borregaard, N., Isolation and primary structure of NGAL, a novel protein associated with human neutrophil gelatinase. J. Biol. Chem. 1993. 268: 1042510432.
  • 4
    Strong, R. K., Bratt, T., Cowland, J. B., Borregaard, N., Wiberg, F. C. and Ewald, A. J., Expression, purification, crystallization and crystallographic characterization of dimeric and monomeric human neutrophil gelatinase associated lipocalin (NGAL). Acta Crystallogr. D 1998. 54: 9395.
  • 5
    Kjeldsen, L., Bainton, D. F., Sengelov, H. and Borregaard, N., Structural and functional heterogeneity among peroxidase-negative granules in human neutrophils: identification of a distinct gelatinase-containing granule subset by combined immunocytochemistry and subcellular fractionation. Blood 1993. 82: 31833191.
  • 6
    Devireddy, L. R., Teodoro, J. G., Richard, F. A. and Green, M. R., Induction of apoptosis by a secreted lipocalin that is transcriptionally regulated by IL-3 deprivation. Science 2001. 293: 829834.
  • 7
    Flo, T. H., Smith, K. D., Sato, S., Rodriguez, D. J., Holmes, M. A., Strong, R. K., Akira, S. et al., Lipocalin 2 mediates an innate immune response to bacterial infection by sequestrating iron. Nature 2004. 432: 917921.
  • 8
    Goetz, D. H., Holmes, M. A., Borregaard, N., Bluhm, M. E., Raymond, K. N. and Strong, R. K., The neutrophil lipocalin NGAL is a bacteriostatic agent that interferes with siderophore-mediated iron acquisition. Mol. Cell 2002. 10: 10331043.
  • 9
    Leng, X., Lin, H., Ding, T., Wang, Y., Wu, Y., Klumpp, S., Sun, T. et al., Lipocalin 2 is required for BCR-ABL-induced tumorigenesis. Oncogene 2008. 27: 61106119.
  • 10
    Miharada, K., Hiroyama, T., Sudo, K., Danjo, I., Nagasawa, T. and Nakamura, Y., Lipocalin 2-mediated growth suppression is evident in human erythroid and monocyte/macrophage lineage cells. J. Cell Physiol. 2008. 215: 526537.
  • 11
    Yang, J., Goetz, D., Li, J. Y., Wang, W., Mori, K., Setlik, D., Du, T. et al., An iron delivery pathway mediated by a lipocalin. Mol. Cell 2002. 10: 10451056.
  • 12
    Bachman, M. A., Miller, V. L. and Weiser, J. N., Mucosal lipocalin 2 has pro-inflammatory and iron-sequestering effects in response to bacterial enterobactin. PLoS Pathog. 2009. 5: e1000622.
  • 13
    Leng, X., Ding, T., Lin, H., Wang, Y., Hu, L., Hu, J., Feig, B. et al., Inhibition of lipocalin 2 impairs breast tumorigenesis and metastasis. Cancer Res. 2009. 69: 85798584.
  • 14
    Berger, T., Togawa, A., Duncan, G. S., Elia, A. J., You-Ten, A., Wakeham, A., Fong, H. E. et al., Lipocalin 2-deficient mice exhibit increased sensitivity to Escherichia coli infection but not to ischemia-reperfusion injury. Proc. Natl. Acad. Sci. U.S.A. 2006. 103: 18341839.
  • 15
    Nairz, M., Theurl, I., Schroll, A., Theurl, M., Fritsche, G., Lindner, E., Seifert, M. et al., Absence of functional Hfe protects mice from invasive Salmonella enterica serovar Typhimurium infection via induction of lipocalin-2. Blood 2009. 114: 36423651.
  • 16
    Bao, G., Clifton, M., Hoette, T. M., Mori, K., Deng, S. X., Qiu, A., Viltard, M. et al., Iron traffics in circulation bound to a siderocalin (Ngal)-catechol complex. Nat. Chem. Biol. 2010. 6: 602609.
  • 17
    Devireddy, L. R., Gazin, C., Zhu, X. and Green, M. R., A cell-surface receptor for lipocalin 24p3 selectively mediates apoptosis and iron uptake. Cell 2005. 123: 12931305.
  • 18
    Mori, K., Lee, H. T., Rapoport, D., Drexler, I. R., Foster, K., Yang, J., Schmidt-Ott, K. M. et al., Endocytic delivery of lipocalin-siderophore-iron complex rescues the kidney from ischemia-reperfusion injury. J. Clin. Invest 2005. 115: 610621.
  • 19
    Borregaard, N. and Cowland, J. B., Neutrophil gelatinase-associated lipocalin, a siderophore-binding eukaryotic protein. Biometals 2006. 19: 211215.
  • 20
    Hvidberg, V., Jacobsen, C., Strong, R. K., Cowland, J. B., Moestrup, S. K. and Borregaard, N., The endocytic receptor megalin binds the iron transporting neutrophil-gelatinase-associated lipocalin with high affinity and mediates its cellular uptake. FEBS Lett. 2005. 579: 773777.
  • 21
    Leng, X., Ding, T. and Arlinghaus, R., Requirement of lipocalin 2 for hematopoietic and solid tumor malignancies. Adv. Enzyme Regul. 2009. 49: 142146.
  • 22
    Hawkins, P. T. and Stephens, L. R., PI3Kgamma is a key regulator of inflammatory responses and cardiovascular homeostasis. Science 2007. 318: 6466.
  • 23
    Entschladen, F. and Zanker, K. S., Locomotion of tumor cells: a molecular comparison to migrating pre- and postmitotic leukocytes. J. Cancer Res. Clin. Oncol. 2000. 126: 671681.
  • 24
    Bachman, M. A., Oyler, J. E., Burns, S. H., Caza, M., Lepine, F., Dozois, C. M. and Weiser, J. N., Klebsiella pneumoniae yersiniabactin promotes respiratory tract infection through evasion of lipocalin 2. Infect. Immun. 2011. 79: 33093316.
  • 25
    Nelson, A. L., Barasch, J. M., Bunte, R. M. and Weiser, J. N., Bacterial colonization of nasal mucosa induces expression of siderocalin, an iron-sequestering component of innate immunity. Cell Microbiol. 2005. 7: 14041417.
  • 26
    Wu, H., Santoni-Rugiu, E., Ralfkiaer, E., Porse, B. T., Moser, C., Hoiby, N., Borregaard, N. et al., Lipocalin 2 is protective against E. coli pneumonia. Respir. Res. 2010. 11: 96.
  • 27
    Ko, G. J., Grigoryev, D. N., Linfert, D., Jang, H. R., Watkins, T., Cheadle, C., Racusen, L. et al., Transcriptional analysis of kidneys during repair from AKI reveals possible roles for NGAL and KIM-1 as biomarkers of AKI-to-CKD transition. Am. J. Physiol. Renal. Physiol. 2010. 298: F14721483.
  • 28
    Lee, S., Park, J. Y., Lee, W. H., Kim, H., Park, H. C., Mori, K. and Suk, K., Lipocalin-2 is an autocrine mediator of reactive astrocytosis. J. Neurosci. 2009. 29: 234249.
  • 29
    Schmidt-Ott, K. M., Mori, K., Kalandadze, A., Li, J. Y., Paragas, N., Nicholas, T., Devarajan, P. et al., Neutrophil gelatinase-associated lipocalin-mediated iron traffic in kidney epithelia. Curr. Opin. Nephrol. Hypertens. 2006. 15: 442449.
  • 30
    Nairz, M., Schroll, A., Sonnweber, T. and Weiss, G., The struggle for iron—a metal at the host-pathogen interface. Cell Microbiol. 2010. 12: 16911702.
  • 31
    Fritsche, G., Nairz, M., Libby, S. J., Fang, F. C. and Weiss, G., Slc11a1 (Nramp1). impairs growth of Salmonella enterica serovar typhimurium in macrophages via. stimulation of lipocalin-2 expression. J. Leukoc. Biol. 2012. 92: 353359.
  • 32
    Takeuchi, O. and Akira, S., Genetic approaches to the study of toll-like receptor function. Microbes Infect. 2002. 4: 887895.
  • 33
    Newton, R. A. and Hogg, N., The human S100 protein MRP-14 is a novel activator of the beta 2 integrin Mac-1 on neutrophils. J. Immunol. 1998. 160: 14271435.
  • 34
    Roth, J., Burwinkel, F., van den Bos, C., Goebeler, M., Vollmer, E. and Sorg, C., MRP8 and MRP14, S-100-like proteins associated with myeloid differentiation, are translocated to plasma membrane and intermediate filaments in a calcium-dependent manner. Blood 1993. 82: 18751883.
  • 35
    Tang, T., Rosenkranz, A., Assmann, K. J., Goodman, M. J., Gutierrez-Ramos, J. C., Carroll, M. C., Cotran, R. S. et al., A role for Mac-1 (CDIIb/CD18) in immune complex-stimulated neutrophil function in vivo: Mac-1 deficiency abrogates sustained Fcgamma receptor-dependent neutrophil adhesion and complement-dependent proteinuria in acute glomerulonephritis. J. Exp. Med. 1997. 186: 18531863.
  • 36
    van den Bos, C., Roth, J., Koch, H. G., Hartmann, M. and Sorg, C., Phosphorylation of MRP14, an S100 protein expressed during monocytic differentiation, modulates Ca(2+)-dependent translocation from cytoplasm to membranes and cytoskeleton. J. Immunol. 1996. 156: 12471254.
  • 37
    Ryckman, C., Vandal, K., Rouleau, P., Talbot, M. and Tessier, P. A., Proinflammatory activities of S100: proteins S100A8, S100A9, and S100A8/A9 induce neutrophil chemotaxis and adhesion. J. Immunol. 2003. 170: 32333242.
  • 38
    Martin, C., Burdon, P. C., Bridger, G., Gutierrez-Ramos, J. C., Williams, T. J. and Rankin, S. M., Chemokines acting via CXCR2 and CXCR4 control the release of neutrophils from the bone marrow and their return following senescence. Immunity 2003. 19: 583593.
  • 39
    Hogg, N., Stewart, M. P., Scarth, S. L., Newton, R., Shaw, J. M., Law, S. K. and Klein, N., A novel leukocyte adhesion deficiency caused by expressed but nonfunctional beta2 integrins Mac-1 and LFA-1. J. Clin. Invest. 1999. 103: 97106.
  • 40
    Allegra, A., Alonci, A., Bellomo, G., Campo, S., Cannavo, A., Penna, G., Russo, S. et al., Increased serum levels of neutrophil gelatinase-associated lipocalin in patients with essential thrombocythemia and polycythemia vera. Leuk. Lymphoma 2011. 52: 101107.
  • 41
    Lippi, G., Salvagno, G. L. and Banfi, G., Serum but not urine concentration of neutrophil gelatinase-associated lipocalin is influenced by acute leukocyte variations. Leuk. Lymphoma 2012. 8: 16431645.
  • 42
    Liu, Z., Yang, A., Wang, Z., Bunting, K. D., Davuluri, G., Green, M. R. and Devireddy, L. R., Multiple apoptotic defects in hematopoietic cells from mice lacking lipocalin 24p3. J. Biol. Chem. 2011. 286: 2060620614.
  • 43
    Feistritzer, C., Mosheimer, B. A., Tancevski, I., Kaneider, N. C., Sturn, D. H., Patsch, J. R. and Wiedermann, C. J., Src tyrosine kinase-dependent migratory effects of antithrombin in leukocytes. Exp. Cell Res. 2005. 305: 214220.
  • 44
    Theurl, I., Mattle, V., Seifert, M., Mariani, M., Marth, C. and Weiss, G., Dysregulated monocyte iron homeostasis and erythropoietin formation in patients with anemia of chronic disease. Blood 2006. 107: 41424148.