See accompanying Commentary: http://dx.doi.org/10.1002/eji.201243184
Dexamethasone promotes tolerance in vivo by enriching CD11cloCD40lo tolerogenic macrophages
Article first published online: 7 NOV 2012
© 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
European Journal of Immunology
Volume 43, Issue 1, pages 219–227, January 2013
How to Cite
Zheng, G., Zhong, S., Geng, Y., Munirathinam, G., Cha, I., Reardon, C., Getz, G. S., van Rooijen, N., Kang, Y., Wang, B. and Chen, A. (2013), Dexamethasone promotes tolerance in vivo by enriching CD11cloCD40lo tolerogenic macrophages. Eur. J. Immunol., 43: 219–227. doi: 10.1002/eji.201242468
- Issue published online: 16 JAN 2013
- Article first published online: 7 NOV 2012
- Accepted manuscript online: 24 SEP 2012 03:47AM EST
- Manuscript Accepted: 17 SEP 2012
- Manuscript Revised: 30 JUL 2012
- Manuscript Received: 16 FEB 2012
- National Institutes of Health. Grant Number: R21HL106340
- Swedish American Health System
- American Diabetes Association
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Fig. S1. MHC II+ cells in the spleen and LNs Balb/c mice.
Fig. S2. Dex depletes CD11chi cells. Dexamethasone crystalline was dissolved in DMSO to 200 mg/mL
Fig. S3. In vivo antigen uptake assay of Dex-enriched macrophages.
Fig. S4. Expression of CD80, CD86, PD-L1, and MHC I on splenic CD11clo macrophages following recall Ag stimulation in vivo.
Fig. S5. Clodronate liposomes selectively deplete the splenic CD11clo macrophages.
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