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Fig. S1. MHC II+ cells in the spleen and LNs Balb/c mice.

Fig. S2. Dex depletes CD11chi cells. Dexamethasone crystalline was dissolved in DMSO to 200 mg/mL

Fig. S3. In vivo antigen uptake assay of Dex-enriched macrophages.

Fig. S4. Expression of CD80, CD86, PD-L1, and MHC I on splenic CD11clo macrophages following recall Ag stimulation in vivo.

Fig. S5. Clodronate liposomes selectively deplete the splenic CD11clo macrophages.

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