Contribution of 4–1BBL on radioresistant cells in providing survival signals through 4–1BB expressed on CD8+ memory T cells in the bone marrow
Article first published online: 20 SEP 2012
© 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
European Journal of Immunology
Volume 42, Issue 11, pages 2861–2874, November 2012
How to Cite
Lin, G. H. Y., Edele, F., Mbanwi, A. N., Wortzman, M. E., Snell, L. M., Vidric, M., Roth, K., Hauser, A. E. and Watts, T. H. (2012), Contribution of 4–1BBL on radioresistant cells in providing survival signals through 4–1BB expressed on CD8+ memory T cells in the bone marrow. Eur. J. Immunol., 42: 2861–2874. doi: 10.1002/eji.201242503
- Issue published online: 29 OCT 2012
- Article first published online: 20 SEP 2012
- Accepted manuscript online: 7 AUG 2012 08:44AM EST
- Manuscript Accepted: 1 AUG 2012
- Manuscript Revised: 29 JUN 2012
- Manuscript Received: 29 FEB 2012
- Canadian Institutes of Health Research. Grant Number: MOP 84419
- Sanofi Pasteur chair in Human Immunology at the University of Toronto
- German Research Foundation. Grant Number: HA5354/4–1
Disclaimer: Supplementary materials have been peer-reviewed but not copyedited.
Figure S1. Defective CD8 T cell recall response to influenza virus in the absence of 4–1BB in mice.
Figure S2. Gating used for analysis of CD8 T cell response after influenza infection.
Figure S3. 4–1BBL+ cells are enriched in the BM CD11c+ MHC-IIneg fraction.
Figure S4. Analysis of chimerism following the generation of radiation bone marrow chimeras.
Figure S5. Gr1+ and B220+ do not overlay and therefore are not pDC.
Figure S6. 4–1BBL is expressed on Gr1lo cells and not B cells in the bone marrow of unimmunized mice.
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