Genetic deletion of the HIF-1α isoform I.1 in T cells enhances antibacterial immunity and improves survival in a murine peritonitis model
Article first published online: 31 JAN 2013
© 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
European Journal of Immunology
Volume 43, Issue 3, pages 655–666, March 2013
How to Cite
Georgiev, P., Belikoff, B. G., Hatfield, S., Ohta, A., Sitkovsky, M. V. and Lukashev, D. (2013), Genetic deletion of the HIF-1α isoform I.1 in T cells enhances antibacterial immunity and improves survival in a murine peritonitis model. Eur. J. Immunol., 43: 655–666. doi: 10.1002/eji.201242765
- Issue published online: 11 MAR 2013
- Article first published online: 31 JAN 2013
- Accepted manuscript online: 4 DEC 2012 07:30AM EST
- Manuscript Accepted: 29 NOV 2012
- Manuscript Revised: 7 NOV 2012
- Manuscript Received: 25 JUN 2012
- NIH. Grant Number: R21 AI068816–01A1
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Figure S1. Expression of I.1 isoform in peritoneal cells.
Figure S2. Scheme of T-cell specific knockout of I.1 isoform.
Figure S3. Intraperitoneal cytokine concentrations in I.1- CD4 T-cell conditional knockdown vs. WT mice after CLP.
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