SEARCH

SEARCH BY CITATION

References

  • 1
    Allen, J. E. and Maizels, R. M., Diversity and dialogue in immunity to helminths. Nat. Rev. Immunol. 2011. 11: 375388.
  • 2
    Maizels, R. M., Balic, A., Gomez-Escobar, N., Nair, M., Taylor, M. D. and Allen, J. E., Helminth parasites—masters of regulation. Immunol. Rev. 2004. 201: 89116.
  • 3
    Maizels, R. M., Infections and allergy—helminths, hygiene and host immune regulation. Curr. Opin. Immunol. 2005. 17: 656661.
  • 4
    Bach, J.-F., The effect of infections on susceptibility to autoimmune and allergic diseases. N. Engl. J. Med. 2002. 347: 911920.
  • 5
    Sakaguchi, S., Ono, M., Setoguchi, R., Yagi, H., Hori, S., Fehervari, Z., Shimizu, J. et al., Foxp3+CD25+CD4+ natural regulatory T cells in dominant self-tolerance and autoimmune disease. Immunol. Rev. 2006. 212: 827.
  • 6
    Belkaid, Y., Regulatory T cells and infection: a dangerous necessity. Nat. Rev. Immunol. 2007. 7: 875888.
  • 7
    Maizels, R. M. and Smith, K. A., Regulatory T cells in infection. Adv. Immunol. 2011. 112: 73136.
  • 8
    Taylor, M. D., Harris, A., Babayan, S. A., Bain, O., Culshaw, A., Allen, J. E. and Maizels, R. M., CTLA-4 and CD4+CD25+ regulatory T cells inhibit protective immunity to filarial parasites in vivo. J. Immunol. 2007. 179: 46264634.
  • 9
    Taylor, M. D., LeGoff, L., Harris, A., Malone, E., Allen, J. E. and Maizels, R. M., Removal of regulatory T cell activity reverses hyporesponsiveness and leads to filarial parasite clearance in vivo. J. Immunol. 2005. 174: 49244933.
  • 10
    Taylor, M. D., van der Werf, N., Harris, A., Graham, A. L., Bain, O., Allen, J. E. and Maizels, R. M., Early recruitment of natural CD4+Foxp3+ Treg cells by infective larvae determines the outcome of filarial infection. Eur. J. Immunol. 2009. 39: 192206.
  • 11
    Blankenhaus, B., Klemm, U., Eschbach, M. L., Sparwasser, T., Huehn, J., Kuhl, A. A., Loddenkemper, C. et al., Strongyloides ratti infection induces expansion of Foxp3+ regulatory T cells that interfere with immune response and parasite clearance in BALB/c mice. J. Immunol. 2011. 186: 42954305.
  • 12
    Hesse, M., Piccirillo, C. A., Belkaid, Y., Prufer, J., Mentink-Kane, M., Leusink, M., Cheever, A. W. et al., The pathogenesis of schistosomiasis is controlled by cooperating IL-10-producing innate effector and regulatory T cells. J. Immunol. 2004. 172: 31573166.
  • 13
    Layland, L. E., Rad, R., Wagner, H. and da Costa, C. U., Immunopathology in schistosomiasis is controlled by antigen-specific regulatory T cells primed in the presence of TLR2. Eur. J. Immunol. 2007. 37: 21742184.
  • 14
    Rausch, S., Huehn, J., Loddenkemper, C., Hepworth, M. R., Klotz, C., Sparwasser, T., Hamann, A. et al., Establishment of nematode infection despite increased Th2 responses and immunopathology after selective depletion of Foxp3+ cells. Eur. J. Immunol. 2009. 39: 30663077.
  • 15
    Wilson, M. S., Taylor, M. D., Balic, A., Finney, C. A., Lamb, J. R. and Maizels, R. M., Suppression of allergic airway inflammation by helminth-induced regulatory T cells. J. Exp. Med. 2005. 202: 11991212.
  • 16
    Simpson, T. R., Quezada, S. A. and Allison, J. P., Regulation of CD4 T cell activation and effector function by inducible costimulator (ICOS). Curr. Opin. Immunol. 2010. 22: 326332.
  • 17
    Crotty, S., Follicular helper CD4 T cells (TFH). Annu. Rev. Immunol. 2011. 29: 621663.
  • 18
    Herman, A. E., Freeman, G. J., Mathis, D. and Benoist, C., CD4+CD25+ T regulatory cells dependent on ICOS promote regulation of effector cells in the prediabetic lesion. J. Exp. Med. 2004. 199: 14791489.
  • 19
    Kornete, M., Sgouroudis, E. and Piccirillo, C. A., ICOS-dependent homeostasis and function of Foxp3+ regulatory T cells in islets of nonobese diabetic mice. J. Immunol. 2012. 188: 10641074.
  • 20
    Prevot, N., Briet, C., Lassmann, H., Tardivel, I., Roy, E., Morin, J., Mak, T. W. et al., Abrogation of ICOS/ICOS ligand costimulation in NOD mice results in autoimmune deviation toward the neuromuscular system. Eur. J. Immunol. 2010. 40: 22672276.
  • 21
    Burmeister, Y., Lischke, T., Dahler, A. C., Mages, H. W., Lam, K. P., Coyle, A. J., Kroczek, R. A. et al., ICOS controls the pool size of effector-memory and regulatory T cells. J. Immunol. 2008. 180: 774782.
  • 22
    Bonhagen, K., Liesenfeld, O., Stadecker, M. J., Hutloff, A., Erb, K., Coyle, A. J., Lipp, M. et al., ICOS+ Th cells produce distinct cytokines in different mucosal immune responses. Eur. J. Immunol. 2003. 33: 392401.
  • 23
    Löhning, M., Hutloff, A., Kallinich, T., Mages, H. W., Bonhagen, K., Radbruch, A., Hamelmann, E. et al., Expression of ICOS in vivo defines CD4+ effector T cells with high inflammatory potential and a strong bias for secretion of interleukin 10. J. Exp. Med. 2003. 197: 181193.
  • 24
    Ito, T., Yang, M., Wang, Y. H., Lande, R., Gregorio, J., Perng, O. A., Qin, X. F. et al., Plasmacytoid dendritic cells prime IL-10-producing T regulatory cells by inducible costimulator ligand. J. Exp. Med. 2007. 204: 105115.
  • 25
    Akbari, O., Freeman, G. J., Meyer, E. H., Greenfield, E. A., Chang, T. T., Sharpe, A. H., Berry, G. et al., Antigen-specific regulatory T cells develop via the ICOS-ICOS-ligand pathway and inhibit allergen-induced airway hyperreactivity. Nat. Med. 2002. 8: 10241032.
  • 26
    Kohyama, M., Sugahara, D., Sugiyama, S., Yagita, H., Okumura, K. and Hozumi, N., Inducible costimulator-dependent IL-10 production by regulatory T cells specific for self-antigen. Proc. Natl. Acad. Sci. USA 2004. 101: 41924197.
  • 27
    Ito, T., Hanabuchi, S., Wang, Y. H., Park, W. R., Arima, K., Bover, L., Qin, F. X. et al., Two functional subsets of FOXP3+ regulatory T cells in human thymus and periphery. Immunity 2008. 28: 870880.
  • 28
    Kopf, M., Coyle, A. J., Schmitz, N., Barner, M., Oxenius, A., Gallimore, A., Gutierrez-Ramos, J. C. et al., Inducible costimulator protein (ICOS) controls T helper cell subset polarization after virus and parasite infection. J. Exp. Med. 2000. 192: 5361.
  • 29
    Wilson, E. H., Zaph, C., Mohrs, M., Welcher, A., Siu, J., Artis, D. and Hunter, C. A., B7RP-1-ICOS interactions are required for optimal infection-induced expansion of CD4+ Th1 and Th2 responses. J. Immunol. 2006. 177: 23652372.
  • 30
    Scales, H., Ierna, M., Gutierrez-Ramos, J., Coyle, A. J., Garside, P. and Lawrence, C. E., Effect of inducible costimulator blockade on the pathological and protective immune responses induced by the gastrointestinal helminth Trichinella spiralis. Eur. J. Immunol. 2004. 34: 28542862.
  • 31
    Loke, P., Zang, X., Hsuan, L., Waitz, R., Locksley, R. M., Allen, J. E. and Allison, J. P., Inducible costimulator is required for type 2 antibody isotype switching but not T helper cell type 2 responses in chronic nematode infection. Proc. Natl. Acad. Sci. USA 2005. 102: 98729877.
  • 32
    Thornton, A. M., Korty, P. E., Tran, D. Q., Wohlfert, E. A., Murray, P. E., Belkaid, Y. and Shevach, E. M., Expression of Helios, an Ikaros transcription factor family member, differentiates thymic-derived from peripherally induced Foxp3+ T regulatory cells. J. Immunol. 2010. 184: 34333441.
  • 33
    Mahajan, S., Cervera, A., MacLeod, M., Fillatreau, S., Perona-Wright, G., Meek, S., Smith, A. et al., The role of ICOS in the development of CD4 T cell help and the reactivation of memory T cells. Eur. J. Immunol. 2007. 37: 17961808.
  • 34
    Rutitzky, L. I., Ozkaynak, E., Rottman, J. B. and Stadecker, M. J., Disruption of the ICOS-B7RP-1 costimulatory pathway leads to enhanced hepatic immunopathology and increased gamma interferon production by CD4 T cells in murine schistosomiasis. Infect. Immun. 2003. 71: 40404044.
  • 35
    Franceschini, D., Paroli, M., Francavilla, V., Videtta, M., Morrone, S., Labbadia, G., Cerino, A. et al., PD-L1 negatively regulates CD4+CD25+Foxp3+ Tregs by limiting STAT-5 phosphorylation in patients chronically infected with HCV. J. Clin. Invest. 2009. 119: 551564.
  • 36
    Grainger, J. R., Smith, K. A., Hewitson, J. P., McSorley, H. J., Harcus, Y., Filbey, K. J., Finney, C. A. et al., Helminth secretions induce de novo T cell Foxp3 expression and regulatory function through the TGF-b pathway. J. Exp. Med. 2010. 207: 23312341.
  • 37
    Barnes, M. J. and Powrie, F., Regulatory T cells reinforce intestinal homeostasis. Immunity 2030. 31: 401411.
  • 38
    King, I. L. and Mohrs, M., IL-4-producing CD4+ T cells in reactive lymph nodes during helminth infection are T follicular helper cells. J. Exp. Med. 2009. 206: 10011007.
  • 39
    Reinhardt, R. L., Liang, H. E. and Locksley, R. M., Cytokine-secreting follicular T cells shape the antibody repertoire. Nat. Immunol. 2009. 10: 385393.
  • 40
    Zaretsky, A. G., Taylor, J. J., King, I. L., Marshall, F. A., Mohrs, M. and Pearce, E. J., T follicular helper cells differentiate from Th2 cells in response to helminth antigens. J. Exp. Med. 2009. 206: 991999.
  • 41
    Finney, C. A., Taylor, M. D., Wilson, M. S. and Maizels, R. M., Expansion and activation of CD4+CD25+ regulatory T cells in Heligmosomoides polygyrus infection. Eur. J. Immunol. 2007. 37: 18741886.
  • 42
    Taylor, M. D., van der Werf, N. and Maizels, R. M., T cells in helminth infection: the regulators and the regulated. Trends Immunol. 2012. 33: 181189.
  • 43
    Sun, J. B., Flach, C. F., Czerkinsky, C. and Holmgren, J., B lymphocytes promote expansion of regulatory T cells in oral tolerance: powerful induction by antigen coupled to cholera toxin B subunit. J. Immunol. 2008. 181: 82788287.
  • 44
    McAdam, A. J., Greenwald, R. J., Levin, M. A., Chernova, T., Malenkovich, N., Ling, V., Freeman, G. J. et al., ICOS is critical for CD40-mediated antibody class switching. Nature 2001. 409: 102105.
  • 45
    Akbari, O., Stock, P., Meyer, E. H., Freeman, G. J., Sharpe, A. H., Umetsu, D. T. and DeKruyff, R. H., ICOS/ICOSL interaction is required for CD4+ invariant NKT cell function and homeostatic survival. J. Immunol. 2008. 180: 54485456.
  • 46
    Totsuka, T., Kanai, T., Iiyama, R., Uraushihara, K., Yamazaki, M., Okamoto, R., Hibi, T. et al., Ameliorating effect of anti-inducible costimulator monoclonal antibody in a murine model of chronic colitis. Gastroenterology 2003. 124: 410421.
  • 47
    Guo, F., Iclozan, C., Suh, W. K., Anasetti, C. and Yu, X. Z., CD28 controls differentiation of regulatory T cells from naive CD4 T cells. J. Immunol. 2008. 181: 22852291.
  • 48
    Gottschalk, R. A., Corse, E. and Allison, J. P., Expression of Helios in peripherally induced Foxp3+ regulatory T cells. J. Immunol. 2012. 188: 976980.
  • 49
    Haribhai, D., Williams, J. B., Jia, S., Nickerson, D., Schmitt, E. G., Edwards, B., Ziegelbauer, J. et al., A requisite role for induced regulatory T cells in tolerance based on expanding antigen receptor diversity. Immunity 2011. 35: 109122.
  • 50
    Verhagen, J. and Wraith, D. C., Comment on “Expression of Helios, an Ikaros transcription factor family member, differentiates thymic-derived from peripherally induced Foxp3+ T regulatory cells”. J. Immunol. 2010. 185: 7129.
  • 51
    Barnes, M. J. and Powrie, F., Regulatory T cells reinforce intestinal homeostasis. Immunity 2009. 31: 401411.
  • 52
    Rubtsov, Y. P., Rasmussen, J. P., Chi, E. Y., Fontenot, J., Castelli, L., Ye, X., Treuting, P. et al., Regulatory T cell-derived interleukin-10 limits inflammation at environmental interfaces. Immunity 2008. 28: 546558.
  • 53
    Elliott, D. E., Setiawan, T., Metwali, A., Blum, A., Urban, J. F. and Weinstock, J. V., Heligmosomoides polygyrus inhibits established colitis in IL-10-deficient mice. Eur. J. Immunol. 2004. 34: 26902698.
  • 54
    Bashir, M. E., Andersen, P., Fuss, I. J., Shi, H. N. and Nagler-Anderson, C., An enteric helminth infection protects against an allergic response to dietary antigen. J. Immunol. 2002. 169: 32843292.
  • 55
    Helmby, H. and Grencis, R. K., Contrasting roles for IL-10 in protective immunity to different life cycle stages of intestinal nematode parasites. Eur. J. Immunol. 2003. 33: 23822390.
  • 56
    Josefowicz, S. Z., Niec, R. E., Kim, H. Y., Treuting, P., Chinen, T., Zheng, Y., Umetsu, D. T. et al., Extrathymically generated regulatory T cells control mucosal TH2 inflammation. Nature 2012. 482: 395399.