Diversification and senescence of Foxp3+ regulatory T cells during experimental autoimmune encephalomyelitis
Article first published online: 9 APR 2013
© 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
European Journal of Immunology
Volume 43, Issue 5, pages 1195–1207, May 2013
How to Cite
Tauro, S., Nguyen, P., Li, B. and Geiger, T. L. (2013), Diversification and senescence of Foxp3+ regulatory T cells during experimental autoimmune encephalomyelitis. Eur. J. Immunol., 43: 1195–1207. doi: 10.1002/eji.201242881
- Issue published online: 25 APR 2013
- Article first published online: 9 APR 2013
- Accepted manuscript online: 25 FEB 2013 02:47AM EST
- Manuscript Accepted: 19 FEB 2013
- Manuscript Revised: 30 JAN 2013
- Manuscript Received: 1 AUG 2012
- National Institutes of Health. Grant Number: R01 AI056153
- American Lebanese Syrian Associated Charities (ALSAC)/St. Jude Children's Research Hospital
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Table S1. Persistence of and KLRG1 expression by transferred KLRG1+ and KLRG1− Treg in C57BL/6 recipients.
Table S2. Treatment of EAE with KLRG1+ and KLRG1− Treg.
Figure S1. Upregulation of KLRG1 on CD4+Foxp3− T cells during EAE.
Figure S2. Gating and sensitivity of Treg transfer studies.
Figure S3. Representative flow cytometry plots of KLRG1+ and KLRG1− Treg transferred into congenic C57BL/6 mice.
Figure S4. BCL2, FAS, and FASL expression on KLRG1+ and KLRG1− Treg.
Figure S5. Co-expression of KLRG1, PD-1, LAG3, and CD103 on Treg during EAE.
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