Meeting Report

γδ T-cell conference 2012: Close encounters for the fifth time

  1. Bruno Silva-Santos1,*,
  2. Wolfgang W. A. Schamel2,
  3. Paul Fisch3,
  4. Matthias Eberl4,*

Article first published online: 18 DEC 2012

DOI: 10.1002/eji.201270101

Issue

European Journal of Immunology

European Journal of Immunology

Volume 42, Issue 12, pages 3101–3105, December 2012

Additional Information

How to Cite

Silva-Santos, B., Schamel, W. W. A., Fisch, P. and Eberl, M. (2012), γδ T-cell conference 2012: Close encounters for the fifth time. Eur. J. Immunol., 42: 3101–3105. doi: 10.1002/eji.201270101

Author Information

  1. 1

    Instituto de Medicina Molecular, Faculdade de Medicina, Universidade de Lisboa, Lisbon, Portugal

  2. 2

    Department of Molecular Immunology, Institute of Biology III, Faculty of Biology, and BIOSS Centre for Biological Signaling Studies and Centre for Chronic Immunodeficiency CCI, University of Freiburg, Germany

  3. 3

    Department of Pathology, Freiburg University Hospital

  4. 4

    Cardiff Institute of Infection and Immunity, School of Medicine, Cardiff University, Cardiff, UK

*Full correspondence: Bruno Silva-Santos, Instituto de Medicina Molecular, Avenida Prof. Egas Moniz, 1649-028 Lisboa, Portugal
Fax. +351-21 798 51 42
e-mail: bssantos@fm.ul.pt
Additional correspondence: Matthias Eberl, Cardiff Institute of Infection and Immunity, Henry Wellcome Building, School of Medicine, Cardiff University, Heath Park, Cardiff CF14 4XN, UK
Fax: +44-29-206 87018
e-mail: eberlm@cf.ac.uk

Publication History

  1. Issue published online: 18 DEC 2012
  2. Article first published online: 18 DEC 2012

Funded by

  • Deutsche Forschungsgemeinschaft. Grant Numbers: FI 458/5-1, EXC294, SFB620, FP7/2007–2013
  • Department of Pathology at the University of Freiburg
  • Centre for Chronic Immunodeficiency
  • local Collaborative Research Centre. Grant Number: CRC 620

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Keywords:

  • γδ T-cell;
  • immunotherapy;
  • infection;
  • T-cell activation;
  • T-cell receptor

Summary

The fifth international γδ T-cell conference was held in Freiburg, Germany, from May 31 to June 2, 2012, bringing together approximately 170 investigators from all over the world. The scientific program covered topics such as thymic development and the mechanisms of ligand recognition and activation, the interaction of γδ T cells with other immune and non-immune cells and its implications for homeostasis, infection, tissue repair and autoimmunity, and the role of γδ T cells in malignancy and their potential for novel immunotherapies. Here we discuss a selection of the oral communications at the conference, and summarise exciting new findings in the field regarding the development, mode of antigen recognition, and responses to microorganisms, viruses and tumours by human and mouse γδ T cells.

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