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Figure S1. IL-10 production in serum, spleen cell culture supernatants and by immune cells of C57BL/C mice infected with blood-stage of P. berghei ANKA infection.

Figure S2. Protective effects of different numbers of IL-10+ and IL-10- B cells adaptively transferred to P. berghei-infected mice and comparison of Bregs isolated from LPS-stimulated B cells and from P. berghei-infected mice.

Figure S3.

Figure S4. Gating strategies used for flow cytometric analysis of IL-10-producing cells, co-cultured CD4+ T and B cells, surface marker expression profiles of IL-10+ and IL-10- B cells and brain NK and CD8+ T cells.

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