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European Journal of Immunology

Cover image for Vol. 38 Issue 4

April 2008

Volume 38, Issue 4

Pages 889–1172

  1. Cover Picture

    1. Top of page
    2. Cover Picture
    3. Editorial
    4. Contents
    5. In this issue
    6. News and EFIS
    7. Viewpoints on Treg
    8. Highlights
    9. Antigen processing
    10. Cellular immune response
    11. Immunity to infection
    12. Immunomodulation
    13. Innate immunity
    14. Molecular immunology
    15. Clinical immunology
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  2. Editorial

    1. Top of page
    2. Cover Picture
    3. Editorial
    4. Contents
    5. In this issue
    6. News and EFIS
    7. Viewpoints on Treg
    8. Highlights
    9. Antigen processing
    10. Cellular immune response
    11. Immunity to infection
    12. Immunomodulation
    13. Innate immunity
    14. Molecular immunology
    15. Clinical immunology
    1. You have free access to this content
  3. Contents

    1. Top of page
    2. Cover Picture
    3. Editorial
    4. Contents
    5. In this issue
    6. News and EFIS
    7. Viewpoints on Treg
    8. Highlights
    9. Antigen processing
    10. Cellular immune response
    11. Immunity to infection
    12. Immunomodulation
    13. Innate immunity
    14. Molecular immunology
    15. Clinical immunology
    1. You have free access to this content
  4. In this issue

    1. Top of page
    2. Cover Picture
    3. Editorial
    4. Contents
    5. In this issue
    6. News and EFIS
    7. Viewpoints on Treg
    8. Highlights
    9. Antigen processing
    10. Cellular immune response
    11. Immunity to infection
    12. Immunomodulation
    13. Innate immunity
    14. Molecular immunology
    15. Clinical immunology
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      In this issue (pages 895–896)

      Version of Record online: 8 APR 2008 | DOI: 10.1002/eji.200890010

  5. News and EFIS

    1. Top of page
    2. Cover Picture
    3. Editorial
    4. Contents
    5. In this issue
    6. News and EFIS
    7. Viewpoints on Treg
    8. Highlights
    9. Antigen processing
    10. Cellular immune response
    11. Immunity to infection
    12. Immunomodulation
    13. Innate immunity
    14. Molecular immunology
    15. Clinical immunology
    1. You have free access to this content
  6. Viewpoints on Treg

    1. Top of page
    2. Cover Picture
    3. Editorial
    4. Contents
    5. In this issue
    6. News and EFIS
    7. Viewpoints on Treg
    8. Highlights
    9. Antigen processing
    10. Cellular immune response
    11. Immunity to infection
    12. Immunomodulation
    13. Innate immunity
    14. Molecular immunology
    15. Clinical immunology
    1. Preface

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    2. The effector functions of regulatory T cells in immune regulation

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      Regulatory T cells and immune computation (pages 903–907)

      Francisco J. Quintana and Irun R. Cohen

      Version of Record online: 8 APR 2008 | DOI: 10.1002/eji.200838143

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    4. The real role of TGF-β in regulatory T cells physiology

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      Critical role of IL-2 and TGF-β in generation, function and stabilization of Foxp3+CD4+ Treg (pages 912–915)

      David A. Horwitz, Song Guo Zheng, Juhua Wang and J. Dixon Gray

      Version of Record online: 8 APR 2008 | DOI: 10.1002/eji.200738109

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      The critical contribution of TGF-β to the induction of Foxp3 expression and regulatory T cell function (pages 915–917)

      Ethan M. Shevach, Dat Q. Tran, Todd S. Davidson and John Andersson

      Version of Record online: 8 APR 2008 | DOI: 10.1002/eji.200738111

    6. Regulatory T cells in Infection and Autoimmunity

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      Human regulatory T cells and autoimmunity (pages 921–924)

      Cristina M. Costantino, Clare M. Baecher-Allan and David A. Hafler

      Version of Record online: 8 APR 2008 | DOI: 10.1002/eji.200738104

    8. The validity of Foxp3 to define human and mouse regulatory T cells

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      Is FOXP3 a bona fide marker for human regulatory T cells? (pages 925–927)

      Maria-Grazia Roncarolo and Silvia Gregori

      Version of Record online: 8 APR 2008 | DOI: 10.1002/eji.200838168

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    10. Clinical applications of regulatory T cells

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    11. You have free access to this content
      Restoring the balance: Harnessing regulatory T cells for therapy in rheumatoid arthritis (pages 934–937)

      Fabian Flores-Borja, Claudia Mauri and Michael R. Ehrenstein

      Version of Record online: 8 APR 2008 | DOI: 10.1002/eji.200738107

  7. Highlights

    1. Top of page
    2. Cover Picture
    3. Editorial
    4. Contents
    5. In this issue
    6. News and EFIS
    7. Viewpoints on Treg
    8. Highlights
    9. Antigen processing
    10. Cellular immune response
    11. Immunity to infection
    12. Immunomodulation
    13. Innate immunity
    14. Molecular immunology
    15. Clinical immunology
    1. Commentary

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    2. Short Communication

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      Sequential phases in the development of Aire-expressing medullary thymic epithelial cells involve distinct cellular input (pages 942–947)

      Andrea J. White, David R. Withers, Sonia M. Parnell, Hamish S. Scott, Daniela Finke, Peter J. L. Lane, Eric J. Jenkinson and Graham Anderson

      Version of Record online: 18 MAR 2008 | DOI: 10.1002/eji.200738052

    3. Frontline

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    4. You have free access to this content
      Liver sinusoidal endothelial cells veto CD8 T cell activation by antigen-presenting dendritic cells (pages 957–967)

      Frank A. Schildberg, Silke I. Hegenbarth, Beatrix Schumak, Andreas Limmer and Percy A. Knolle

      Version of Record online: 26 MAR 2008 | DOI: 10.1002/eji.200738060

  8. Antigen processing

    1. Top of page
    2. Cover Picture
    3. Editorial
    4. Contents
    5. In this issue
    6. News and EFIS
    7. Viewpoints on Treg
    8. Highlights
    9. Antigen processing
    10. Cellular immune response
    11. Immunity to infection
    12. Immunomodulation
    13. Innate immunity
    14. Molecular immunology
    15. Clinical immunology
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      N-terminal flanking residues of a diabetes-associated GAD65 determinant are necessary for activation of antigen-specific T cells in diabetes-resistant mice (pages 968–976)

      Yang D. Dai, Kent P. Jensen, Idania Marrero, Ningli Li, Anthony Quinn and Eli E. Sercarz

      Version of Record online: 8 APR 2008 | DOI: 10.1002/eji.200737703

  9. Cellular immune response

    1. Top of page
    2. Cover Picture
    3. Editorial
    4. Contents
    5. In this issue
    6. News and EFIS
    7. Viewpoints on Treg
    8. Highlights
    9. Antigen processing
    10. Cellular immune response
    11. Immunity to infection
    12. Immunomodulation
    13. Innate immunity
    14. Molecular immunology
    15. Clinical immunology
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      Notch signaling is necessary for GATA3 function in the initiation of T cell development (pages 977–985)

      Katsuto Hozumi, Naoko Negishi, Izumi Tsuchiya, Natsumi Abe, Ken-ichi Hirano, Daisuke Suzuki, Masayuki Yamamoto, James D. Engel and Sonoko Habu

      Version of Record online: 26 MAR 2008 | DOI: 10.1002/eji.200737688

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      Defective positive selection results in T cell lymphopenia and increased autoimmune diabetes in ADAP-deficient BDC2.5-C57BL/6 mice (pages 986–994)

      Liangxing Zou, Felipe Mendez, Natalia Martin-Orozco and Erik J. Peterson

      Version of Record online: 26 MAR 2008 | DOI: 10.1002/eji.200737881

    3. Short Communication

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      Proliferation and interleukin 5 production by CD8hiCD57+ T cells (pages 995–1000)

      Lee K. Chong, Rebecca J. Aicheler, Sian Llewellyn-Lacey, Peter Tomasec, Paul Brennan and Eddie C. Y. Wang

      Version of Record online: 26 MAR 2008 | DOI: 10.1002/eji.200737687

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      Glycolipid-activated NKT cells support the induction of persistent plasma cell responses and antibody titers (pages 1001–1011)

      T. Scott Devera, Hemangi B. Shah, Gillian A. Lang and Mark L. Lang

      Version of Record online: 18 MAR 2008 | DOI: 10.1002/eji.200738000

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      Distinct subsets of human invariant NKT cells differentially regulate T helper responses via dendritic cells (pages 1012–1023)

      Tian-Yi Liu, Yasushi Uemura, Motoharu Suzuki, Yayoi Narita, Shinya Hirata, Hideki Ohyama, Osamu Ishihara and Sho Matsushita

      Version of Record online: 18 MAR 2008 | DOI: 10.1002/eji.200737838

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      CD137 ligand reverse signaling has multiple functions in human dendritic cells during an adaptive immune response (pages 1024–1032)

      Undine Lippert, Karolin Zachmann, David M. Ferrari, Herbert Schwarz, Edgar Brunner, A. H. M. Mahbub-ul Latif, Christine Neumann and Afsaneh Soruri

      Version of Record online: 8 APR 2008 | DOI: 10.1002/eji.200737800

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      Superior induction of anti-tumor CTL immunity by extended peptide vaccines involves prolonged, DC-focused antigen presentation (pages 1033–1042)

      Martijn S. Bijker, Susan J. F. van den Eeden, Kees L. Franken, Cornelis J. M. Melief, Sjoerd H. van der Burg and Rienk Offringa

      Version of Record online: 18 MAR 2008 | DOI: 10.1002/eji.200737995

  10. Immunity to infection

    1. Top of page
    2. Cover Picture
    3. Editorial
    4. Contents
    5. In this issue
    6. News and EFIS
    7. Viewpoints on Treg
    8. Highlights
    9. Antigen processing
    10. Cellular immune response
    11. Immunity to infection
    12. Immunomodulation
    13. Innate immunity
    14. Molecular immunology
    15. Clinical immunology
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      Dendritic cell expression of the Notch ligand jagged2 is not essential for Th2 response induction in vivo (pages 1043–1049)

      Alan G. F. Worsley, Salome LeibundGut-Landmann, Emma Slack, Li-Kun Phng, Holger Gerhardt, Caetano Reis e Sousa and Andrew S. MacDonald

      Version of Record online: 18 MAR 2008 | DOI: 10.1002/eji.200737335

    2. Short Communication

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      Preservation of a critical epitope core region is associated with the high degree of flaviviral cross-reactivity exhibited by a dengue-specific CD4+ T cell clone (pages 1050–1057)

      Edward Moran, Cameron Simmons, Nguyen Vinh Chau, Kerstin Luhn, Bridget Wills, Nguyen Phuong Dung, Le Thi Thu Thao, Tran Tinh Hien, Jeremy Farrar, Sarah Rowland-Jones and Tao Dong

      Version of Record online: 26 MAR 2008 | DOI: 10.1002/eji.200737699

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      Viruses induce high expression of BAFF by salivary gland epithelial cells through TLR- and type-I IFN-dependent and -independent pathways (pages 1058–1064)

      Marc Ittah, Corinne Miceli-Richard, Jacques-Eric Gottenberg, Jérémie Sellam, Pierre Eid, Pierre Lebon, Coralie Pallier, Christine Lepajolec and Xavier Mariette

      Version of Record online: 18 MAR 2008 | DOI: 10.1002/eji.200738013

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      Coxiella burnetii, the agent of Q fever, stimulates an atypical M2 activation program in human macrophages (pages 1065–1070)

      Marie Benoit, Bernadette Barbarat, Alain Bernard, Daniel Olive and Jean-Louis Mege

      Version of Record online: 18 MAR 2008 | DOI: 10.1002/eji.200738067

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      A novel form of NF-κB is induced by Leishmania infection: Involvement in macrophage gene expression (pages 1071–1081)

      David J. Gregory, Marianne Godbout, Irazú Contreras, Geneviève Forget and Martin Olivier

      Version of Record online: 26 MAR 2008 | DOI: 10.1002/eji.200737586

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      CXCR3 determines strain susceptibility to murine cerebral malaria by mediating T lymphocyte migration toward IFN-γ-induced chemokines (pages 1082–1095)

      Philippe E. Van den Steen, Katrien Deroost, Ilse Van Aelst, Nathalie Geurts, Erik Martens, Sofie Struyf, Catherine Q. Nie, Diana S. Hansen, Patrick Matthys, Jo Van Damme and Ghislain Opdenakker

      Version of Record online: 26 MAR 2008 | DOI: 10.1002/eji.200737906

  11. Immunomodulation

    1. Top of page
    2. Cover Picture
    3. Editorial
    4. Contents
    5. In this issue
    6. News and EFIS
    7. Viewpoints on Treg
    8. Highlights
    9. Antigen processing
    10. Cellular immune response
    11. Immunity to infection
    12. Immunomodulation
    13. Innate immunity
    14. Molecular immunology
    15. Clinical immunology
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      Contrasting cytoskeletal regulation of MHC class II peptide presentation by human B cells or dendritic cells (pages 1096–1105)

      Alix Delaguillaumie, Viviana Marin-Esteban, Niclas Setterblad, Laurence Jeanson Leh, Eric Assier, Catherine Gelin, Dominique Charron, Anne Galy and Nuala Mooney

      Version of Record online: 26 MAR 2008 | DOI: 10.1002/eji.200737455

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      Interleukin-10 regulates TNF-α−converting enzyme (TACE/ADAM-17) involving a TIMP-3 dependent and independent mechanism (pages 1106–1117)

      Fionula M. Brennan, Patricia Green, Parisa Amjadi, Heidi J. Robertshaw, Montserrat Alvarez-Iglesias and Masao Takata

      Version of Record online: 26 MAR 2008 | DOI: 10.1002/eji.200737821

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      Th17 development and autoimmune arthritis in the absence of reactive oxygen species (pages 1118–1126)

      Annie George-Chandy, Inger Nordström, Erik Nygren, Ing-Marie Jonsson, Jorge Postigo, Laurence Vincent Collins and Kristina Eriksson

      Version of Record online: 26 MAR 2008 | DOI: 10.1002/eji.200737348

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      Dendritic cells in colonic patches and iliac lymph nodes are essential in mucosal IgA induction following intrarectal administration via CCR7 interaction (pages 1127–1137)

      Ah-Young Lee, Sun-Young Chang, Jung-Im Kim, Hye-Ran Cha, Myoung Ho Jang, Masafumi Yamamoto and Mi-Na Kweon

      Version of Record online: 18 MAR 2008 | DOI: 10.1002/eji.200737442

  12. Innate immunity

    1. Top of page
    2. Cover Picture
    3. Editorial
    4. Contents
    5. In this issue
    6. News and EFIS
    7. Viewpoints on Treg
    8. Highlights
    9. Antigen processing
    10. Cellular immune response
    11. Immunity to infection
    12. Immunomodulation
    13. Innate immunity
    14. Molecular immunology
    15. Clinical immunology
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      TLR4 and S1P receptors cooperate to enhance inflammatory cytokine production in human gingival epithelial cells (pages 1138–1147)

      Mehmet A. Eskan, Beate G. Rose, Manjunatha R. Benakanakere, Qun Zeng, Daisuke Fujioka, Michael H. Martin, Menq-Jer Lee and Denis F. Kinane

      Version of Record online: 8 APR 2008 | DOI: 10.1002/eji.200737898

  13. Molecular immunology

    1. Top of page
    2. Cover Picture
    3. Editorial
    4. Contents
    5. In this issue
    6. News and EFIS
    7. Viewpoints on Treg
    8. Highlights
    9. Antigen processing
    10. Cellular immune response
    11. Immunity to infection
    12. Immunomodulation
    13. Innate immunity
    14. Molecular immunology
    15. Clinical immunology
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      Recombinase-deficient T cell development by selective accumulation of CD3 into lipid rafts (pages 1148–1156)

      Denise Ferrera, Maddalena Panigada, Simona Porcellini and Fabio Grassi

      Version of Record online: 18 MAR 2008 | DOI: 10.1002/eji.200737917

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      Characterisation of murine MICL (CLEC12A) and evidence for an endogenous ligand (pages 1157–1163)

      Elwira Pyż, Cristal Huysamen, Andrew S. J. Marshall, Siamon Gordon, Philip R. Taylor and Gordon D. Brown

      Version of Record online: 18 MAR 2008 | DOI: 10.1002/eji.200738057

  14. Clinical immunology

    1. Top of page
    2. Cover Picture
    3. Editorial
    4. Contents
    5. In this issue
    6. News and EFIS
    7. Viewpoints on Treg
    8. Highlights
    9. Antigen processing
    10. Cellular immune response
    11. Immunity to infection
    12. Immunomodulation
    13. Innate immunity
    14. Molecular immunology
    15. Clinical immunology
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      Chimpanzee CD4+ T cells are relatively insensitive to HIV-1 envelope-mediated inhibition of CD154 up-regulation (pages 1164–1172)

      Erik Rutjens, Joost Vermeulen, Babs Verstrepen, Sam Hofman, Jan M. Prins, Indresh Srivastava, Jonathan L. Heeney and Gerrit Koopman

      Version of Record online: 26 MAR 2008 | DOI: 10.1002/eji.200737792

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