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European Journal of Immunology

Cover image for European Journal of Immunology

April 2010

Volume 40, Issue 4

Pages 913–1218

  1. Cover Picture

    1. Top of page
    2. Cover Picture
    3. Contents
    4. In this issue
    5. News and EFIS
    6. Book Review
    7. Highlights
    8. Cellular immune response
    9. Immunity to infection
    10. Immunomodulation
    11. Innate immunity
    12. Molecular immunology
    13. Leukocyte signaling
    14. Correction
    1. You have free access to this content
      Cover Picture: Eur. J. Immunol. 4/10

      Bo-Shiou Lin, Pei-Yun Tsai, Wan-Yun Hsieh, Hsiao-Wei Tsao, Meng-Wei Liu, Roland Grenningloh, Li-Fang Wang, I-Cheng Ho and Shi-Chuen Miaw

      Article first published online: 14 APR 2010 | DOI: 10.1002/eji.201090019

  2. Contents

    1. Top of page
    2. Cover Picture
    3. Contents
    4. In this issue
    5. News and EFIS
    6. Book Review
    7. Highlights
    8. Cellular immune response
    9. Immunity to infection
    10. Immunomodulation
    11. Innate immunity
    12. Molecular immunology
    13. Leukocyte signaling
    14. Correction
    1. You have free access to this content
      Contents – Eur. J. Immunol. 04/10 (pages 913–917)

      Article first published online: 14 APR 2010 | DOI: 10.1002/eji.201090015

  3. In this issue

    1. Top of page
    2. Cover Picture
    3. Contents
    4. In this issue
    5. News and EFIS
    6. Book Review
    7. Highlights
    8. Cellular immune response
    9. Immunity to infection
    10. Immunomodulation
    11. Innate immunity
    12. Molecular immunology
    13. Leukocyte signaling
    14. Correction
    1. You have free access to this content
      In this issue (pages 918–919)

      Article first published online: 14 APR 2010 | DOI: 10.1002/eji.201090016

  4. News and EFIS

    1. Top of page
    2. Cover Picture
    3. Contents
    4. In this issue
    5. News and EFIS
    6. Book Review
    7. Highlights
    8. Cellular immune response
    9. Immunity to infection
    10. Immunomodulation
    11. Innate immunity
    12. Molecular immunology
    13. Leukocyte signaling
    14. Correction
    1. You have free access to this content
  5. Book Review

    1. Top of page
    2. Cover Picture
    3. Contents
    4. In this issue
    5. News and EFIS
    6. Book Review
    7. Highlights
    8. Cellular immune response
    9. Immunity to infection
    10. Immunomodulation
    11. Innate immunity
    12. Molecular immunology
    13. Leukocyte signaling
    14. Correction
    1. You have free access to this content
  6. Highlights

    1. Top of page
    2. Cover Picture
    3. Contents
    4. In this issue
    5. News and EFIS
    6. Book Review
    7. Highlights
    8. Cellular immune response
    9. Immunity to infection
    10. Immunomodulation
    11. Innate immunity
    12. Molecular immunology
    13. Leukocyte signaling
    14. Correction
    1. Review

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    2. Commentaries

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    3. You have free access to this content
    4. Frontline

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    5. You have free access to this content
      Loss of DNAM-1 contributes to CD8+ T-cell exhaustion in chronic HIV-1 infection (pages 949–954)

      Marina Cella, Rachel Presti, William Vermi, Kerry Lavender, Emma Turnbull, Christina Ochsenbauer-Jambor, John C. Kappes, Guido Ferrari, Lisa Kessels, Ian Williams, CHAVI Clinical Core B, Andrew J. McMichael, Barton F. Haynes, Persephone Borrow, Marco Colonna and the NIAID Center for HIV/AIDS Vaccine Immunology

      Article first published online: 3 MAR 2010 | DOI: 10.1002/eji.200940234

  7. Cellular immune response

    1. Top of page
    2. Cover Picture
    3. Contents
    4. In this issue
    5. News and EFIS
    6. Book Review
    7. Highlights
    8. Cellular immune response
    9. Immunity to infection
    10. Immunomodulation
    11. Innate immunity
    12. Molecular immunology
    13. Leukocyte signaling
    14. Correction
    1. Research Article

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      Thymic stromal lymphopoietin induces early human B-cell proliferation and differentiation (pages 955–965)

      Ferenc A. Scheeren, Anja U. van Lent, Maho Nagasawa, Kees Weijer, Hergen Spits, Nicolas Legrand and Bianca Blom

      Article first published online: 1 FEB 2010 | DOI: 10.1002/eji.200939419

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      Parenchymal cells critically curtail cytotoxic T-cell responses by inducing Bim-mediated apoptosis (pages 966–975)

      Anton Gruber, Michael A. Cannarile, Cedric Cheminay, Christine Ried, Peggy Marconi, Georg Häcker and Thomas Brocker

      Article first published online: 1 FEB 2010 | DOI: 10.1002/eji.200939485

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      Bystander stimulation of activated CD4+ T cells of unrelated specificity following a booster vaccination with tetanus toxoid (pages 976–985)

      Gianfranco Di Genova, Natalia Savelyeva, Amy Suchacki, Stephen M. Thirdborough and Freda K. Stevenson

      Article first published online: 26 JAN 2010 | DOI: 10.1002/eji.200940017

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      Involvement of CD91 and scavenger receptors in Hsp70-facilitated activation of human antigen-specific CD4+ memory T cells (pages 986–997)

      Nadja Fischer, Markus Haug, William W. Kwok, Hubert Kalbacher, Dorothee Wernet, Guenther E. Dannecker and Ursula Holzer

      Article first published online: 25 JAN 2010 | DOI: 10.1002/eji.200939738

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      Impaired CD4+ T-cell proliferation and effector function correlates with repressive histone methylation events in a mouse model of severe sepsis (pages 998–1010)

      William F. Carson, Karen A. Cavassani, Toshihiro Ito, Matthew Schaller, Makoto Ishii, Yali Dou and Steven L. Kunkel

      Article first published online: 1 FEB 2010 | DOI: 10.1002/eji.200939739

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      Targeted inhibition of IL-10-secreting CD25 Treg via p38 MAPK suppression in cancer immunotherapy (pages 1011–1021)

      Kozo Ohkusu-Tsukada, Masahiro Toda, Heiichiro Udono, Yutaka Kawakami and Kimimasa Takahashi

      Article first published online: 1 FEB 2010 | DOI: 10.1002/eji.200939513

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      Uptake of apoptotic DC converts immature DC into tolerogenic DC that induce differentiation of Foxp3+ Treg (pages 1022–1035)

      Rahul Kushwah, Jing Wu, Jordan R. Oliver, George Jiang, Jinyi Zhang, Katherine A. Siminovitch and Jim Hu

      Article first published online: 25 JAN 2010 | DOI: 10.1002/eji.200939782

  8. Immunity to infection

    1. Top of page
    2. Cover Picture
    3. Contents
    4. In this issue
    5. News and EFIS
    6. Book Review
    7. Highlights
    8. Cellular immune response
    9. Immunity to infection
    10. Immunomodulation
    11. Innate immunity
    12. Molecular immunology
    13. Leukocyte signaling
    14. Correction
    1. Short Communication

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      Characterization of an HLA-C-restricted CTL response in chronic HIV infection (pages 1036–1041)

      Azure T. Makadzange, Geraldine Gillespie, Tao Dong, Peter Kiama, Job Bwayo, Joshua Kimani, Frank Plummer, Philippa Easterbrook and Sarah L. Rowland-Jones

      Article first published online: 26 JAN 2010 | DOI: 10.1002/eji.200939634

    2. Research Article

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      CCL20/CCR6 blockade enhances immunity to RSV by impairing recruitment of DC (pages 1042–1052)

      Lara E. Kallal, Matthew A. Schaller, Dennis M. Lindell, Sergio A. Lira and Nicholas W. Lukacs

      Article first published online: 25 JAN 2010 | DOI: 10.1002/eji.200939778

    3. Short Communication

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      Involvement of CD8+ T cells in protective immunity against murine blood-stage infection with Plasmodium yoelii 17XL strain (pages 1053–1061)

      Takashi Imai, Jianying Shen, Bin Chou, Xuefeng Duan, Liping Tu, Kohhei Tetsutani, Chikako Moriya, Hidekazu Ishida, Shinjiro Hamano, Chikako Shimokawa, Hajime Hisaeda and Kunisuke Himeno

      Article first published online: 25 JAN 2010 | DOI: 10.1002/eji.200939525

    4. Research Article

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      The effect of placental malaria infection on cord blood and maternal immunoregulatory responses at birth (pages 1062–1072)

      Katie L. Flanagan, Alice Halliday, Sarah Burl, Katja Landgraf, Ya Jankey Jagne, Fatou Noho-Konteh, John Townend, David J. C. Miles, Marianne van der Sande, Hilton Whittle and Sarah Rowland-Jones

      Article first published online: 28 DEC 2009 | DOI: 10.1002/eji.200939638

  9. Immunomodulation

    1. Top of page
    2. Cover Picture
    3. Contents
    4. In this issue
    5. News and EFIS
    6. Book Review
    7. Highlights
    8. Cellular immune response
    9. Immunity to infection
    10. Immunomodulation
    11. Innate immunity
    12. Molecular immunology
    13. Leukocyte signaling
    14. Correction
    1. Short Communication

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      Human β-defensin 3 has immunosuppressive activity in vitro and in vivo (pages 1073–1078)

      Fiona Semple, Sheila Webb, Hsin-Ni Li, Hetal B. Patel, Mauro Perretti, Ian J. Jackson, Mohini Gray, Donald J. Davidson and Julia R. Dorin

      Article first published online: 26 JAN 2010 | DOI: 10.1002/eji.200940041

    2. Research Article

      You have full text access to this OnlineOpen article
      Complement C5a regulates IL-17 by affecting the crosstalk between DC and γδ T cells in CLP-induced sepsis (pages 1079–1088)

      Ruonan Xu, Renxi Wang, Gencheng Han, Jianan Wang, Guojiang Chen, Liyan Wang, Xia Li, Renfeng Guo, Beifen Shen and Yan Li

      Article first published online: 5 FEB 2010 | DOI: 10.1002/eji.200940015

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      In vitro-induced Th17 cells fail to induce inflammation in vivo and show an impaired migration into inflamed sites (pages 1089–1098)

      Marko Janke, Michael Peine, Alexia Nass, Lars Morawietz, Alf Hamann and Alexander Scheffold

      Article first published online: 25 JAN 2010 | DOI: 10.1002/eji.200939487

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      Co-expression of TNFR2 and CD25 identifies more of the functional CD4+FOXP3+ regulatory T cells in human peripheral blood (pages 1099–1106)

      Xin Chen, Jeffrey J. Subleski, Ryoko Hamano, O. M. Zack Howard, Robert H. Wiltrout and Joost J. Oppenheim

      Article first published online: 1 FEB 2010 | DOI: 10.1002/eji.200940022

  10. Innate immunity

    1. Top of page
    2. Cover Picture
    3. Contents
    4. In this issue
    5. News and EFIS
    6. Book Review
    7. Highlights
    8. Cellular immune response
    9. Immunity to infection
    10. Immunomodulation
    11. Innate immunity
    12. Molecular immunology
    13. Leukocyte signaling
    14. Correction
    1. Research Article

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      Continuous CD27 triggering in vivo strongly reduces NK cell numbers (pages 1107–1117)

      Veerle De Colvenaer, Sylvie Taveirne, Jörg Hamann, Alex M. de Bruin, Magda De Smedt, Tom Taghon, Bart Vandekerckhove, Jean Plum, Rene van Lier and Georges Leclercq

      Article first published online: 5 FEB 2010 | DOI: 10.1002/eji.200939251

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      The antimicrobial peptide LL-37 modulates the inflammatory and host defense response of human neutrophils (pages 1118–1126)

      Sadek M. Alalwani, Johannes Sierigk, Christian Herr, Olaf Pinkenburg, Richard Gallo, Claus Vogelmeier and Robert Bals

      Article first published online: 5 FEB 2010 | DOI: 10.1002/eji.200939275

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      The cyclin-dependent kinase inhibitor R-roscovitine down-regulates Mcl-1 to override pro-inflammatory signalling and drive neutrophil apoptosis (pages 1127–1138)

      Andrew E. Leitch, Nicola A. Riley, Tara A. Sheldrake, Michela Festa, Sarah Fox, Rodger Duffin, Christopher Haslett and Adriano G. Rossi

      Article first published online: 1 FEB 2010 | DOI: 10.1002/eji.200939664

  11. Molecular immunology

    1. Top of page
    2. Cover Picture
    3. Contents
    4. In this issue
    5. News and EFIS
    6. Book Review
    7. Highlights
    8. Cellular immune response
    9. Immunity to infection
    10. Immunomodulation
    11. Innate immunity
    12. Molecular immunology
    13. Leukocyte signaling
    14. Correction
    1. Research Article

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    2. You have free access to this content
      Ectopic GC in the thymus of myasthenia gravis patients show characteristics of normal GC (pages 1150–1161)

      Neta S. Zuckerman, Wendy A. Howard, Jacky Bismuth, Kate Gibson, Hanna Edelman, Sonia Berrih-Aknin, Deborah Dunn-Walters and Ramit Mehr

      Article first published online: 26 JAN 2010 | DOI: 10.1002/eji.200939914

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      CXCL4-induced monocyte survival, cytokine expression, and oxygen radical formation is regulated by sphingosine kinase 1 (pages 1162–1173)

      Brigitte Kasper, Supandi Winoto-Morbach, Jessica Mittelstädt, Ernst Brandt, Stefan Schütze and Frank Petersen

      Article first published online: 26 JAN 2010 | DOI: 10.1002/eji.200939703

    4. Research Article

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      SUMOylation attenuates c-Maf-dependent IL-4 expression (pages 1174–1184)

      Bo-Shiou Lin, Pei-Yun Tsai, Wan-Yun Hsieh, Hsiao-Wei Tsao, Meng-Wei Liu, Roland Grenningloh, Li-Fang Wang, I-Cheng Ho and Shi-Chuen Miaw

      Article first published online: 1 FEB 2010 | DOI: 10.1002/eji.200939788

    5. Short Communication

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      The DC-SIGN family member LSECtin is a novel ligand of CD44 on activated T cells (pages 1185–1191)

      Li Tang, Juntao Yang, Xiaoming Tang, Wantao Ying, Xiaohong Qian and Fuchu He

      Article first published online: 1 FEB 2010 | DOI: 10.1002/eji.200939936

  12. Leukocyte signaling

    1. Top of page
    2. Cover Picture
    3. Contents
    4. In this issue
    5. News and EFIS
    6. Book Review
    7. Highlights
    8. Cellular immune response
    9. Immunity to infection
    10. Immunomodulation
    11. Innate immunity
    12. Molecular immunology
    13. Leukocyte signaling
    14. Correction
    1. Research Article

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      Differential phosphorylation of functional tyrosines in CD19 modulates B-lymphocyte activation (pages 1192–1204)

      Nobuko Ishiura, Hiroko Nakashima, Rei Watanabe, Yoshihiro Kuwano, Takahiro Adachi, Yoshimasa Takahashi, Takeshi Tsubata, Hitoshi Okochi, Kunihiko Tamaki, Thomas F. Tedder and Manabu Fujimoto

      Article first published online: 25 JAN 2010 | DOI: 10.1002/eji.200939848

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      FcεRI β-chain ITAM amplifies PI3K-signaling to ensure synergistic degranulation response via FcεRI and adenosine receptors (pages 1205–1217)

      Satoshi Nunomura, Yasuhiro Gon, Tetsuro Yoshimaru, Junichi Kashiwakura, Toshiaki Kawakami and Chisei Ra

      Article first published online: 25 JAN 2010 | DOI: 10.1002/eji.200939651

  13. Correction

    1. Top of page
    2. Cover Picture
    3. Contents
    4. In this issue
    5. News and EFIS
    6. Book Review
    7. Highlights
    8. Cellular immune response
    9. Immunity to infection
    10. Immunomodulation
    11. Innate immunity
    12. Molecular immunology
    13. Leukocyte signaling
    14. Correction
    1. You have free access to this content
      Correction: In this issue (page 1218)

      Article first published online: 14 APR 2010 | DOI: 10.1002/eji.201090014

      This article corrects:

      In this issue

      Vol. 40, Issue 1, 6–7, Article first published online: 30 DEC 2009

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