European Journal of Immunology

Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim

Cover image for Vol. 41 Issue 12

December 2011

Volume 41, Issue 12

Pages i–ii, 3383–3667

  1. Cover Picture

    1. Top of page
    2. Cover Picture
    3. Editorial Board
    4. Editorial
    5. Contents
    6. In this issue
    7. News and EFIS
    8. Obituary
    9. Meeting Report
    10. Highlights
    11. Molecular immunology
    12. Cellular immune response
    13. Immunity to infection
    14. Immunomodulation
    15. Molecular immunology
    16. Innate immunity
    17. Molecular immunology
    18. Acknowledgement
    1. Cover Picture: Eur. J. Immunol. 12/11

      Jennifer L. Marshall, Yang Zhang, Lalit Pallan, Mei-Chi Hsu, Mahmood Khan, Adam F. Cunningham, Ian C. M. MacLennan and Kai-Michael Toellner

      Article first published online: 28 NOV 2011 | DOI: 10.1002/eji.201190077

  2. Editorial Board

    1. Top of page
    2. Cover Picture
    3. Editorial Board
    4. Editorial
    5. Contents
    6. In this issue
    7. News and EFIS
    8. Obituary
    9. Meeting Report
    10. Highlights
    11. Molecular immunology
    12. Cellular immune response
    13. Immunity to infection
    14. Immunomodulation
    15. Molecular immunology
    16. Innate immunity
    17. Molecular immunology
    18. Acknowledgement
    1. You have free access to this content
      Editorial Board: Eur. J. Immunol. 12/11

      Article first published online: 28 NOV 2011 | DOI: 10.1002/eji.201190078

  3. Editorial

    1. Top of page
    2. Cover Picture
    3. Editorial Board
    4. Editorial
    5. Contents
    6. In this issue
    7. News and EFIS
    8. Obituary
    9. Meeting Report
    10. Highlights
    11. Molecular immunology
    12. Cellular immune response
    13. Immunity to infection
    14. Immunomodulation
    15. Molecular immunology
    16. Innate immunity
    17. Molecular immunology
    18. Acknowledgement
    1. You have free access to this content
      Tributes, conferences and listening to authors (pages i–ii)

      Cate Livingstone

      Article first published online: 28 NOV 2011 | DOI: 10.1002/eji.201190079

  4. Contents

    1. Top of page
    2. Cover Picture
    3. Editorial Board
    4. Editorial
    5. Contents
    6. In this issue
    7. News and EFIS
    8. Obituary
    9. Meeting Report
    10. Highlights
    11. Molecular immunology
    12. Cellular immune response
    13. Immunity to infection
    14. Immunomodulation
    15. Molecular immunology
    16. Innate immunity
    17. Molecular immunology
    18. Acknowledgement
    1. Contents – Eur. J. Immunol. 12/11 (pages 3383–3387)

      Article first published online: 28 NOV 2011 | DOI: 10.1002/eji.201190070

  5. In this issue

    1. Top of page
    2. Cover Picture
    3. Editorial Board
    4. Editorial
    5. Contents
    6. In this issue
    7. News and EFIS
    8. Obituary
    9. Meeting Report
    10. Highlights
    11. Molecular immunology
    12. Cellular immune response
    13. Immunity to infection
    14. Immunomodulation
    15. Molecular immunology
    16. Innate immunity
    17. Molecular immunology
    18. Acknowledgement
    1. In this issue (pages 3388–3389)

      Article first published online: 28 NOV 2011 | DOI: 10.1002/eji.201190071

  6. News and EFIS

    1. Top of page
    2. Cover Picture
    3. Editorial Board
    4. Editorial
    5. Contents
    6. In this issue
    7. News and EFIS
    8. Obituary
    9. Meeting Report
    10. Highlights
    11. Molecular immunology
    12. Cellular immune response
    13. Immunity to infection
    14. Immunomodulation
    15. Molecular immunology
    16. Innate immunity
    17. Molecular immunology
    18. Acknowledgement
    1. You have free access to this content
      HIV-1: From escapism to conservatism (pages 3390–3393)

      Tomáš Hanke and Andrew J. McMichael

      Article first published online: 28 NOV 2011 | DOI: 10.1002/eji.201190072

    2. You have free access to this content
      The 2011 Nobel Prize in Physiology or Medicine: Honor, sadness and lessons (page 3393)

      Catherine Sautès-Fridman

      Article first published online: 28 NOV 2011 | DOI: 10.1002/eji.201190073

  7. Obituary

    1. Top of page
    2. Cover Picture
    3. Editorial Board
    4. Editorial
    5. Contents
    6. In this issue
    7. News and EFIS
    8. Obituary
    9. Meeting Report
    10. Highlights
    11. Molecular immunology
    12. Cellular immune response
    13. Immunity to infection
    14. Immunomodulation
    15. Molecular immunology
    16. Innate immunity
    17. Molecular immunology
    18. Acknowledgement
    1. Ralph M. Steinman (1943–2011) (pages 3394–3395)

      Article first published online: 28 NOV 2011 | DOI: 10.1002/eji.201190074

  8. Meeting Report

    1. Top of page
    2. Cover Picture
    3. Editorial Board
    4. Editorial
    5. Contents
    6. In this issue
    7. News and EFIS
    8. Obituary
    9. Meeting Report
    10. Highlights
    11. Molecular immunology
    12. Cellular immune response
    13. Immunity to infection
    14. Immunomodulation
    15. Molecular immunology
    16. Innate immunity
    17. Molecular immunology
    18. Acknowledgement
    1. Immunological consequences of arthropod vector-derived salivary factors (pages 3396–3400)

      Wolfgang W. Leitner, Adriana Costero-Saint Denis and Tonu Wali

      Article first published online: 28 NOV 2011 | DOI: 10.1002/eji.201190075

  9. Highlights

    1. Top of page
    2. Cover Picture
    3. Editorial Board
    4. Editorial
    5. Contents
    6. In this issue
    7. News and EFIS
    8. Obituary
    9. Meeting Report
    10. Highlights
    11. Molecular immunology
    12. Cellular immune response
    13. Immunity to infection
    14. Immunomodulation
    15. Molecular immunology
    16. Innate immunity
    17. Molecular immunology
    18. Acknowledgement

    1. Review

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      HIV/AIDS: 30 Years of progress and future challenges (pages 3401–3411)

      M. Scott Killian and Jay A. Levy

      Article first published online: 28 NOV 2011 | DOI: 10.1002/eji.201142082

    2. Mini-Review

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      CCL2: A potential prognostic marker and target of anti-inflammatory strategy in HIV/AIDS pathogenesis (pages 3412–3418)

      Abdul W. Ansari, Hans Heiken, Dirk Meyer-Olson and Reinhold E. Schmidt

      Article first published online: 10 NOV 2011 | DOI: 10.1002/eji.201141676

    3. Commentary

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      Regulating inflammation: ADAM8 – a new player in the game (pages 3419–3422)

      Alexander Zarbock and Jan Rossaint

      Article first published online: 28 NOV 2011 | DOI: 10.1002/eji.201142196

    4. Frontline

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      DOCK8 is essential for T-cell survival and the maintenance of CD8+ T-cell memory (pages 3423–3435)

      Teresa Lambe, Greg Crawford, Andy L. Johnson, Tanya L. Crockford, Tiphaine Bouriez-Jones, Aisling M. Smyth, Trung H. M. Pham, Qian Zhang, Alexandra F. Freeman, Jason G. Cyster, Helen C. Su and Richard J. Cornall

      Article first published online: 10 NOV 2011 | DOI: 10.1002/eji.201141759

  10. Molecular immunology

    1. Top of page
    2. Cover Picture
    3. Editorial Board
    4. Editorial
    5. Contents
    6. In this issue
    7. News and EFIS
    8. Obituary
    9. Meeting Report
    10. Highlights
    11. Molecular immunology
    12. Cellular immune response
    13. Immunity to infection
    14. Immunomodulation
    15. Molecular immunology
    16. Innate immunity
    17. Molecular immunology
    18. Acknowledgement

    1. Frontline

      The metalloprotease ADAM8 is associated with and regulates the function of the adhesion receptor PSGL-1 through ERM proteins (pages 3436–3442)

      Maria Domínguez-Luis, Amalia Lamana, Jesús Vazquez, Rósula García-Navas, Faustino Mollinedo, Francisco Sánchez-Madrid, Federico Díaz-González and Ana Urzainqui

      Article first published online: 10 NOV 2011 | DOI: 10.1002/eji.201141764

  11. Cellular immune response

    1. Top of page
    2. Cover Picture
    3. Editorial Board
    4. Editorial
    5. Contents
    6. In this issue
    7. News and EFIS
    8. Obituary
    9. Meeting Report
    10. Highlights
    11. Molecular immunology
    12. Cellular immune response
    13. Immunity to infection
    14. Immunomodulation
    15. Molecular immunology
    16. Innate immunity
    17. Molecular immunology
    18. Acknowledgement

    1. Research Article

      Differential role for CD277 as a co-regulator of the immune signal in T and NK cells (pages 3443–3454)

      Nassima Messal, Emilie Mamessier, Aude Sylvain, Javier Celis-Gutierrez, Marie-Laure Thibult, Bruno Chetaille, Guylène Firaguay, Sonia Pastor, Yves Guillaume, Qian Wang, Ivan Hirsch, Jacques A. Nunès and Daniel Olive

      Article first published online: 3 NOV 2011 | DOI: 10.1002/eji.201141404

    2. CD4+Foxp3+ regulatory T cells suppress γδ T-cell effector functions in a model of T-cell-induced mucosal inflammation (pages 3455–3466)

      Ekaterina Yurchenko, Megan K. Levings and Ciriaco A. Piccirillo

      Article first published online: 10 NOV 2011 | DOI: 10.1002/eji.201141814

    3. Expansion of a restricted residual host Treg-cell repertoire is dependent on IL-2 following experimental autologous hematopoietic stem transplantation (pages 3467–3478)

      Allison L. Bayer, Jackeline Chirinos, Cecilia Cabello, Jing Yang, Takaji Matsutani, Thomas R. Malek and Robert B. Levy

      Article first published online: 31 OCT 2011 | DOI: 10.1002/eji.201141611

    4. Similar inflammatory DC maturation signatures induced by TNF or Trypanosoma brucei antigens instruct default Th2-cell responses (pages 3479–3494)

      Katrien Pletinckx, Benoit Stijlemans, Vladimir Pavlovic, Regina Laube, Carolin Brandl, Susanne Kneitz, Alain Beschin, Patrick De Baetselier and Manfred B. Lutz

      Article first published online: 3 NOV 2011 | DOI: 10.1002/eji.201141631

    5. Persistence of IL-2 expressing Th17 cells in healthy humans and experimental autoimmune uveitis (pages 3495–3505)

      Cheng-Rong Yu, Hyun-Mee Oh, Nady Golestaneh, Ahjoku Amadi-Obi, Yun S. Lee, Amarachi Eseonu, Rashid M. Mahdi and Charles E. Egwuagu

      Article first published online: 27 OCT 2011 | DOI: 10.1002/eji.201141654

    6. Short Communication

      Early B blasts acquire a capacity for Ig class switch recombination that is lost as they become plasmablasts (pages 3506–3512)

      Jennifer L. Marshall, Yang Zhang, Lalit Pallan, Mei-Chi Hsu, Mahmood Khan, Adam F. Cunningham, Ian C. M. MacLennan and Kai-Michael Toellner

      Article first published online: 10 NOV 2011 | DOI: 10.1002/eji.201141762

  12. Immunity to infection

    1. Top of page
    2. Cover Picture
    3. Editorial Board
    4. Editorial
    5. Contents
    6. In this issue
    7. News and EFIS
    8. Obituary
    9. Meeting Report
    10. Highlights
    11. Molecular immunology
    12. Cellular immune response
    13. Immunity to infection
    14. Immunomodulation
    15. Molecular immunology
    16. Innate immunity
    17. Molecular immunology
    18. Acknowledgement

    1. Research Article

      Lack of IL-7 and IL-15 signaling affects interferon-γ production by, more than survival of, small intestinal intraepithelial memory CD8+ T cells (pages 3513–3528)

      Dmitry Isakov, Amiran Dzutsev, Jay A. Berzofsky and Igor M. Belyakov

      Article first published online: 28 NOV 2011 | DOI: 10.1002/eji.201141453

    2. CD4+Foxp3+ regulatory T cells mediate Toxoplasma gondii-induced T-cell suppression through an IL-2-related mechanism but independently of IL-10 (pages 3529–3541)

      Eda P. Tenorio, Jacquelina Fernández, Carlos Castellanos, Jonadab E. Olguín and Rafael Saavedra

      Article first published online: 20 OCT 2011 | DOI: 10.1002/eji.201141507

    3. Research Article

      Optimizing HIV-1-specific CD8+ T-cell induction by recombinant BCG in prime-boost regimens with heterologous viral vectors (pages 3542–3552)

      Richard Hopkins, Anne Bridgeman, Charles Bourne, Alice Mbewe-Mvula, Jerald C. Sadoff, Gerald W. Both, Joan Joseph, John Fulkerson and Tomáš Hanke

      Article first published online: 26 OCT 2011 | DOI: 10.1002/eji.201141962

  13. Immunomodulation

    1. Top of page
    2. Cover Picture
    3. Editorial Board
    4. Editorial
    5. Contents
    6. In this issue
    7. News and EFIS
    8. Obituary
    9. Meeting Report
    10. Highlights
    11. Molecular immunology
    12. Cellular immune response
    13. Immunity to infection
    14. Immunomodulation
    15. Molecular immunology
    16. Innate immunity
    17. Molecular immunology
    18. Acknowledgement

    1. Research Article

      Enhancement of anti-tumor immunity through local modulation of CTLA-4 and GITR by dendritic cells (pages 3553–3563)

      Scott K. Pruitt, David Boczkowski, Nicole de Rosa, N. Rebecca Haley, Michael A. Morse, Douglas S. Tyler, Jens Dannull and Smita Nair

      Article first published online: 26 OCT 2011 | DOI: 10.1002/eji.201141383

    2. Human tumor-induced and naturally occurring Treg cells differentially affect NK cells activated by either IL-2 or target cells (pages 3564–3573)

      Christoph Bergmann, Clarissa A. Wild, Mustafa Narwan, Ramin Lotfi, Stephan Lang and Sven Brandau

      Article first published online: 26 OCT 2011 | DOI: 10.1002/eji.201141532

    3. NOD mice contain an elevated frequency of iNKT17 cells that exacerbate diabetes (pages 3574–3585)

      Yannick Simoni, Anne-Sophie Gautron, Lucie Beaudoin, Linh-Chi Bui, Marie-Laure Michel, Xavier Coumoul, Gérard Eberl, Maria Leite-de-Moraes and Agnès Lehuen

      Article first published online: 10 NOV 2011 | DOI: 10.1002/eji.201141751

    4. HMGB1 blockade attenuates experimental autoimmune myocarditis and suppresses Th17-cell expansion (pages 3586–3595)

      Zhaoliang Su, Caixia Sun, Chenglin Zhou, Yanfang Liu, Haitao Zhu, Siamak Sandoghchian, Dong Zheng, Tianqing Peng, Yu Zhang, Zhijun Jiao, Shengjun Wang and Huaxi Xu

      Article first published online: 10 NOV 2011 | DOI: 10.1002/eji.201141879

    5. Short Communication

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      Pre-differentiated human committed T-lymphoid progenitors promote peripheral T-cell re-constitution after stem cell transplantation in immunodeficient mice (pages 3596–3603)

      Matthias Eyrich, Susanne C. Schreiber, Gernot Wollny, Hendrik Ziegler, Ramona Schlenker, Katharina Koch-Büttner, Matthias Wölfl, Paul G. Schlegel and Karin Schilbach

      Article first published online: 24 OCT 2011 | DOI: 10.1002/eji.201141561

    6. Research Article

      Differentiation of human thymic regulatory T cells at the double positive stage (pages 3604–3614)

      Helena Nunes-Cabaço, Íris Caramalho, Nuno Sepúlveda and Ana E. Sousa

      Article first published online: 24 OCT 2011 | DOI: 10.1002/eji.201141614

  14. Molecular immunology

    1. Top of page
    2. Cover Picture
    3. Editorial Board
    4. Editorial
    5. Contents
    6. In this issue
    7. News and EFIS
    8. Obituary
    9. Meeting Report
    10. Highlights
    11. Molecular immunology
    12. Cellular immune response
    13. Immunity to infection
    14. Immunomodulation
    15. Molecular immunology
    16. Innate immunity
    17. Molecular immunology
    18. Acknowledgement

    1. Research Article

      Intratumor OX40 stimulation inhibits IRF1 expression and IL-10 production by Treg cells while enhancing CD40L expression by effector memory T cells (pages 3615–3626)

      Alessia Burocchi, Paola Pittoni, Andrea Gorzanelli, Mario P. Colombo and Silvia Piconese

      Article first published online: 10 NOV 2011 | DOI: 10.1002/eji.201141700

  15. Innate immunity

    1. Top of page
    2. Cover Picture
    3. Editorial Board
    4. Editorial
    5. Contents
    6. In this issue
    7. News and EFIS
    8. Obituary
    9. Meeting Report
    10. Highlights
    11. Molecular immunology
    12. Cellular immune response
    13. Immunity to infection
    14. Immunomodulation
    15. Molecular immunology
    16. Innate immunity
    17. Molecular immunology
    18. Acknowledgement

    1. Short Communication

      Intrinsic expression of Nod2 in CD4+ T lymphocytes is not necessary for the development of cell-mediated immunity and host resistance to Toxoplasma gondii (pages 3627–3631)

      Braulia C. Caetano, Amlan Biswas, Djalma S. Lima-Junior, Luciana Benevides, Tiago W. P. Mineo, Catarina V. Horta, Kyoung-Hee Lee, Joao S. Silva, Ricardo T. Gazzinelli, Dario S. Zamboni and Koichi S. Kobayashi

      Article first published online: 10 NOV 2011 | DOI: 10.1002/eji.201141876

  16. Molecular immunology

    1. Top of page
    2. Cover Picture
    3. Editorial Board
    4. Editorial
    5. Contents
    6. In this issue
    7. News and EFIS
    8. Obituary
    9. Meeting Report
    10. Highlights
    11. Molecular immunology
    12. Cellular immune response
    13. Immunity to infection
    14. Immunomodulation
    15. Molecular immunology
    16. Innate immunity
    17. Molecular immunology
    18. Acknowledgement

    1. Research Article

      Glycotranscriptome study reveals an enzymatic switch modulating glycosaminoglycan synthesis during B-cell development and activation (pages 3632–3644)

      Sophie Duchez, Virginie Pascal, Nadine Cogné, Chantal Jayat-Vignoles, Raymond Julien and Michel Cogné

      Article first published online: 10 NOV 2011 | DOI: 10.1002/eji.201140865

    2. Elevated BCR signaling and decreased survival of Lyn-deficient transitional and follicular B cells (pages 3645–3655)

      Andrew J. Gross, Irina Proekt and Anthony L. DeFranco

      Article first published online: 10 NOV 2011 | DOI: 10.1002/eji.201141708

    3. IL-7 determines the homeostatic fitness of T cells by distinct mechanisms at different signalling thresholds in vivo (pages 3656–3666)

      Claire Pearson, Ana Silva, Manoj Saini and Benedict Seddon

      Article first published online: 3 NOV 2011 | DOI: 10.1002/eji.201141514

    4. Palmitoylation of MICA, a ligand for NKG2D, mediates its recruitment to membrane microdomains and promotes its shedding (pages 3667–3676)

      Sonia Agüera-González, Catharina C. Gross, Lola Fernández-Messina, Omodele Ashiru, Gloria Esteso, Howard C. Hang, Hugh T. Reyburn, Eric O. Long and Mar Valés-Gómez

      Article first published online: 3 NOV 2011 | DOI: 10.1002/eji.201141645

  17. Acknowledgement

    1. Top of page
    2. Cover Picture
    3. Editorial Board
    4. Editorial
    5. Contents
    6. In this issue
    7. News and EFIS
    8. Obituary
    9. Meeting Report
    10. Highlights
    11. Molecular immunology
    12. Cellular immune response
    13. Immunity to infection
    14. Immunomodulation
    15. Molecular immunology
    16. Innate immunity
    17. Molecular immunology
    18. Acknowledgement
    1. Acknowledgements (pages 3666–3667)

      Article first published online: 28 NOV 2011 | DOI: 10.1002/eji.201190076

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