Regioselective Double Organic Functionalization of Polyoxotungstates through Electrophilic Addition of Aromatic Isocyanates to [P2W17O61(SnR)]7–


  • Dedicated to Professor Michael T. Pope on the occasion of his 80th birthday


The direct attachment of several different organic molecules to a single polyoxometalate remains a challenge in the field of functionalized polyoxometalates. In this paper, we show that an organotin-functionalized Dawson-type polyoxotungstate [P2W17O61(SnR)]7– reacts with aromatic isocyanates ArNCO to yield new doubly functionalized compounds [P2W17O61(SnR)(CONHAr)]6–. Both organic moieties, Ar and R, can be varied independently; we have tested nine Ar and three R groups. Therefore, this synthetic methodology represents a way to graft two distinct functional molecules directly onto a polyoxometalate.