• Homogeneous catalysis;
  • Epoxidation;
  • Molybdenum;
  • Tungsten;
  • Cycloalkenes


The catalytic activity of [Cp*2M2O5] (M = Mo, W; Cp* = pentamethylcyclopentadienyl) for the homogeneous epoxidation of a solution of cyclooctene in MeCN/toluene follows the order Mo >> W when using tert-butyl hydroperoxide (TBHP)/decane as oxidant, in contrast to the inverse order (W >> Mo) when using aqueous H2O2 as oxidant. The catalytic activity for the Mo system strongly depends on the solvent used to deliver the oxidant (TBHP/decane >> TBHP/H2O). The low activity of the W system is also decreased when using TBHP/water in place of TBHP/decane. For both metals, H2O2/H2O is a better oxidant than TBHP/H2O. However, whereas the Mo-based catalyst is much more active for the TBHP/decane epoxidation in spite of the lower TBHP oxidizing power (TBHP/decane > H2O2/H2O > TBHP/H2O), the W-based system is much more active for the H2O2/H2O epoxidation in spite of the negative effect of water (H2O2/H2O > TBHP/decane > TBHP/H2O). The kinetic profile of the TBHP/decane epoxidation process is affected by product inhibition. Initial rate measurements show that the rate law is first order with respect to substrate and has saturation behavior with respect to the oxidant.