Synthesis, X-ray Crystallography, Spectroelectrochemistry and Computational Studies on Potential Copper-Based Radiopharmaceuticals (pages 3549–3560)
Jason P. Holland, Peter J. Barnard, David Collison, Jonathan R. Dilworth, Ruth Edge, Jennifer C. Green, Julia M. Heslop, Eric J. L. McInnes, Christoph G. Salzmann and Amber L. Thompson
Version of Record online: 24 JUN 2008 | DOI: 10.1002/ejic.200800413
A new class of metal(II) bis(thiosemicarbazonato) complexes have been characterised as potential hypoxia-selective imagingagents for use in positron emission tomography. Spectroelectrochemical experiments have been used to study the reaction of the copper(I) anion with dioxygen and provide information on the mechanism of hypoxia selectivity.