Sila-α-galbanone and Analogues: Synthesis and Olfactory Characterization of Silicon-Containing Derivatives of the Galbanum Odorant α-Galbanone (pages 4394–4407)
Steffen Dörrich, Anna Ulmer, Christoph Mahler, Christian Burschka, Johannes A. Baus, Reinhold Tacke, An Chai, Changming Ding, Yue Zou, Gerhard Brunner, Andreas Goeke and Philip Kraft
Article first published online: 5 AUG 2014 | DOI: 10.1002/ejic.201402597
Sila-α-galbanone, sila-α-spirogalbanone, and sila-nor-α-galbanone (sila-analogues of α-galbanone, α-spirogalbanone, and nor-α-galbanone) were synthesized starting from Me2SiCl2, (CH2=CH)2SiCl2, and Me2(CH2=CH)SiCl, respectively. These sila-analogues proved to be less volatile and thus more tenacious than the parent carbon compounds while also providing insight into structure–odor correlations.