Short Communication

A Polymer-Supported Phosphoramide as a Lewis-Base Catalyst for the Catalytic Aldol Reaction

  1. Robert A. Flowers II1,
  2. Xin Xu2,
  3. Cody Timmons2,
  4. Guigen Li2

Article first published online: 28 JUN 2004

DOI: 10.1002/ejoc.200400228

Issue

European Journal of Organic Chemistry

European Journal of Organic Chemistry

Volume 2004, Issue 14, pages 2988–2990, July 2004

Additional Information

How to Cite

Flowers, R., Xu, X., Timmons, C. and Li, G. (2004), A Polymer-Supported Phosphoramide as a Lewis-Base Catalyst for the Catalytic Aldol Reaction. European Journal of Organic Chemistry, 2004: 2988–2990. doi: 10.1002/ejoc.200400228

Author Information

  1. 1

    Department of Chemistry, Lehigh University, Bethlehem, PA 18015, USA

  2. 2

    Department of Chemistry and Biochemistry, Texas Tech University, Lubbock, TX 79409-1061, USA

Publication History

  1. Issue published online: 28 JUN 2004
  2. Article first published online: 28 JUN 2004
  3. Manuscript Received: 2 APR 2004

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Keywords:

  • HMPA-type derivative;
  • Aldol reactions;
  • Polymeric phosphoramide

Graphical Abstract

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Abstract

The aldol reactions between trichlorosilyl enol ethers and aldehydes were catalyzed by an environmentally benign polymer-supported phosphoramide organocatalyst. Eight examples are reported with moderate to good chemical yields and stereoselectivity. Significant rate enhancements were observed. (© Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2004)

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