Carbene Rearrangements, Part LXIV; for Part LXIII, see: J.-L. Mieusset, U. H. Brinker, J. Org. Chem.2006, 71, 6975–6982. Carbenes in Constrained Systems, Part XI; for Part X, see: M. G. Rosenberg, U. H. Brinker, Adv. Phys. Org. Chem.2005, 40, 1–47.
1099-0690/asset/2046_left.gif?v=1&s=0ec9ed8843eb5403f667ad940f5a1c68cb5ef011)
1099-0690/asset/2046_right.gif?v=1&s=b2caf576ff74b55a6a4748bd86a910901b664c52)
Microreview
Constrained Carbenes†
Article first published online: 12 OCT 2006
DOI: 10.1002/ejoc.200600547
Copyright © 2006 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Additional Information
How to Cite
Rosenberg, M. G. and Brinker, U. H. (2006), Constrained Carbenes. European Journal of Organic Chemistry, 2006: 5423–5440. doi: 10.1002/ejoc.200600547
- †
Publication History
- Issue published online: 4 DEC 2006
- Article first published online: 12 OCT 2006
- Manuscript Received: 26 JUN 2006
- Abstract
- Article
- References
- Cited By
Keywords:
- Carbenes;
- Reactive intermediates;
- Host–guest systems;
- Supramolecular chemistry
Graphical Abstract
Abstract
Carbenes traditionally have been used for cyclopropane synthesis but little else, since their reactions are difficult to control. However, the burgeoning discipline of supramolecular carbene chemistry—reactions in which highly reactive, divalent carbon intermediates are generated within the confines of host compounds—is making steady progress towards solving this problem. Various carbenes generated within cyclodextrins, hemicarcerands, and zeolites demonstrate increased selectivities and lifetimes since their usual decay pathways are blocked. (© Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2006)