Get access

Carbonylative Suzuki–Miyaura Coupling of Arylboronic Acids with Aryl Iodides Catalyzed by the MCM-41-Supported Bidentate Phosphane Palladium(II) Complex



The first heterogeneous carbonylative Suzuki–Miyaura cross-coupling reaction of arylboronic acids with aryl iodides under an atmospheric pressure of carbon monoxide has been achieved in anisole at 80 °C in the presence of a catalytic amount of an MCM-41-supported bidentate phosphane palladium(II) complex (MCM-41-2P-PdII), yielding unsymmetrical biaryl ketones in good-to-high yields. This polymeric palladium catalyst exhibited higher activity and selectivity than [PdCl2(PPh3)2] and can be reused at least 10 times without any decrease in activity. (© Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2009)