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Full Paper
Formamidines – Versatile Ligands for Zinc-Catalyzed Hydrosilylation and Iron-Catalyzed Epoxidation Reactions
Article first published online: 16 JUL 2010
DOI: 10.1002/ejoc.201000648
Copyright © 2010 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Additional Information
How to Cite
Enthaler, S., Schröder, K., Inoue, S., Eckhardt, B., Junge, K., Beller, M. and Drieß, M. (2010), Formamidines – Versatile Ligands for Zinc-Catalyzed Hydrosilylation and Iron-Catalyzed Epoxidation Reactions. Eur. J. Org. Chem., 2010: 4893–4901. doi: 10.1002/ejoc.201000648
Publication History
- Issue published online: 23 AUG 2010
- Article first published online: 16 JUL 2010
- Manuscript Received: 7 MAY 2010
Funded by
- Deutsche Forschungsgemeinschaft (DFG)
- Graduiertenkolleg 1213
- Max-Buchner-Forschungsstiftung(DECHEMA)
- Abstract
- Article
- References
- Cited By
Keywords:
- Homogeneous catalysis;
- Zinc;
- Iron;
- Amidine ligands;
- Hydrosilylation;
- Epoxidation
Abstract
In the present study the abilities of catalysts modified by formamidine ligands have been examined in the zinc-catalyzed hydrosilylation of ketones and the iron-catalyzed epoxidation of stilbene. In case of hydrosilylation diethylzinc combined with easily accessible formamidine ligands allow for the efficient reduction of various aryl and alkyl ketones. By using a convenient in situ catalyst system high turnover frequencies up to more than 1.000 h–1 and a broad functional group tolerance were achieved. Moreover, the formamidine ligands were successfully applied in the iron-catalyzed epoxidation of stilbene with hydrogen peroxide in good yield and chemoselectivity.