Synthesis of Phosphonylated and Thiolated Indenones by Manganese(III)-Mediated Addition of Phosphorus- and Sulfur-Centered Radicals to 1,3-Diarylpropynones

Authors

  • Jun Zhou,

    1. Key Laboratory of Organic Synthesis of Jiangsu Province,College of Chemistry and Chemical Engineering, SuzhouUniversity, 199 Renai Street, Suzhou, Jiangsu 215123, China, Fax: +86-512-65880335
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  • Guang-Liang Zhang,

    1. Key Laboratory of Organic Synthesis of Jiangsu Province,College of Chemistry and Chemical Engineering, SuzhouUniversity, 199 Renai Street, Suzhou, Jiangsu 215123, China, Fax: +86-512-65880335
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  • Jian-Ping Zou,

    1. Key Laboratory of Organic Synthesis of Jiangsu Province,College of Chemistry and Chemical Engineering, SuzhouUniversity, 199 Renai Street, Suzhou, Jiangsu 215123, China, Fax: +86-512-65880335
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  • Wei Zhang

    1. Department of Chemistry, University of Massachusetts Boston, 100 Morrissey Boulevard, Boston, MA 02125, USA, Fax: +1-617-287-6030
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Abstract

Phosphorus- or sulfur-centered radicals generated from the reaction of manganese(III) acetate with dialkyl phosphonates or arylthiols undergo selective additions to conjugated alkynes followed by cyclization and rearomatization to afford 2-phosphonyl- or 2-thioaryl-substituted indenones in fair to good yields.

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