Preparation of Chiral Multifunctional Thiourea–Phosphanes and Synthesis of Chiral Allylic Phosphites and Phosphane Oxides through Asymmetric Allylic Substitution Reactions of Morita–Baylis–Hillman Carbonates

Authors

  • Hong-Ping Deng,

    1. State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 354 Fenglin Road, Shanghai 200032, China, Fax: +86-21-64166128
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  • Min Shi

    1. State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 354 Fenglin Road, Shanghai 200032, China, Fax: +86-21-64166128
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Abstract

We developed a synthetic method to prepare chiral multifunctional thiourea–phosphane catalysts for the asymmetric allylic substitution reaction of Morita–Baylis–Hillman carbonates with diphenyl phosphite or diphenylphosphane oxide to give allylic phosphites and allylic phosphane oxides in high yields with excellent enantioselectivity.

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