Get access

Concise Total Synthesis of Permethylated Anigopreissin A, a New Benzofuryl Resveratrol Dimer

Authors

  • Lucia Chiummiento,

    1. Dipartimento di Chimica “Antonio Mario Tamburro”, Università degli Studi della Basilicata, Via dell'Ateneo Lucano 10, 85100 Potenza, Italy, Fax: +39-0971-205678
    Search for more papers by this author
  • Maria Funicello,

    1. Dipartimento di Chimica “Antonio Mario Tamburro”, Università degli Studi della Basilicata, Via dell'Ateneo Lucano 10, 85100 Potenza, Italy, Fax: +39-0971-205678
    Search for more papers by this author
  • Maria Teresa Lopardo,

    1. Dipartimento di Chimica “Antonio Mario Tamburro”, Università degli Studi della Basilicata, Via dell'Ateneo Lucano 10, 85100 Potenza, Italy, Fax: +39-0971-205678
    Search for more papers by this author
  • Paolo Lupattelli,

    1. Dipartimento di Chimica “Antonio Mario Tamburro”, Università degli Studi della Basilicata, Via dell'Ateneo Lucano 10, 85100 Potenza, Italy, Fax: +39-0971-205678
    Search for more papers by this author
  • Sabine Choppin,

    1. Laboratoire de Stéréochimie, Ecole de Chimie Polymères et Matériaux (ECPM), Université de Strasbourg CNRS UMR 7509, 25 Rue Becquerel, 67087 Strasbourg cedex 2, France
    Search for more papers by this author
  • Françoise Colobert

    1. Laboratoire de Stéréochimie, Ecole de Chimie Polymères et Matériaux (ECPM), Université de Strasbourg CNRS UMR 7509, 25 Rue Becquerel, 67087 Strasbourg cedex 2, France
    Search for more papers by this author

  • Dedicated to Professor Alberto Brandi on the occasion of his 60th birthday

Abstract

The versatile preparation of permethylated anigopreissin A (1) has been accomplished from methyl 3,5-dihydroxybenzoate. The key steps of the synthesis are sequential Sonogashira and Suzuki cross-couplings for the construction of the 2,3-diarylbenzo[b]furan moiety and Wittig olefination for the introduction of the styryl group.

Ancillary