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Keywords:

  • Copper;
  • Fluorine;
  • Arenes;
  • Trifluoromethylation

Abstract

Development of transition-metal-catalyzed trifluoromethylation of arene substrates under mild reaction conditions has attracted great attention in the past few years. Among the many methods developed, copper-mediated trifluororomethylation has made significant progress and is the subject of this minireview.