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Short Communication
Amination of Aryl Halides by Using an Environmentally Benign, Recyclable Copper Catalyst
Article first published online: 9 AUG 2012
DOI: 10.1002/ejoc.201200787
Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Additional Information
How to Cite
Huang, M., Wang, L., Zhu, X., Mao, Z., Kuang, D. and Wan, Y. (2012), Amination of Aryl Halides by Using an Environmentally Benign, Recyclable Copper Catalyst. Eur. J. Org. Chem., 2012: 4897–4901. doi: 10.1002/ejoc.201200787
Publication History
- Issue published online: 3 SEP 2012
- Article first published online: 9 AUG 2012
- Manuscript Received: 13 JUN 2012
Funded by
- National Natural Science Foundation of China. Grant Numbers: 20872182, 20802095
Keywords:
- Copper;
- Carbohydrates;
- Homogeneous catalysis;
- Amination;
- Sustainable chemistry
Abstract
The combination of CuSO4 with naturally occurring sucrose in a biodegradable aqueous solution of PEG-200 has been confirmed as a novel, recyclable, and environmentally benign homogeneous catalyst system for the direct amination of aryl halides with NH3·H2O. Electron-rich, electron-poor, and even ortho-substituted aryl bromides and iodides could be aminated to provide the desired primary arylamines in high yields at 90 °C without the need of an inert atmosphere.