SEARCH

SEARCH BY CITATION

Keywords:

  • Homogeneous catalysis;
  • Nickel;
  • C–C coupling;
  • C–H functionali­zation;
  • Arylation;
  • Biaryls

Abstract

Nickel catalysis for biaryl coupling reactions has received significant attention as a less expensive and less toxic alternative to “standard” palladium catalysis. Here we describe recent developments in nickel-catalyzed biaryl coupling methodology, along with mechanistic studies and applications. In particular we focus on nickel-catalyzed coupling reactions in which “unreactive” bonds such as C–H, C–O, and C–C bonds are converted into biaryl moieties.