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Keywords:

  • Synthetic methods;
  • Nitrogen heterocycles;
  • Sulfur heterocycles;
  • Peri­cyclic reactions

Abstract

The ring opening of 3-nitro-4-(phenylsulfonyl)thiophene with amines and proper modification of the resulting 1,3-diene enables a simple and versatile approach to N-fused pyrroles of both synthetic and biological interest through 1,6-H shift followed by 6π 1,5-electrocyclization. This protocol is effectively driven to the isolated pyrroles by an easy aromatization.