These authors contributed equally.
Thiophostone-Derived Brønsted Acids in the Organocatalyzed Transfer Hydrogenation of Quinolines: Influence of the P-Stereogenicity
Article first published online: 24 OCT 2013
Copyright © 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
European Journal of Organic Chemistry
Volume 2014, Issue 1, pages 188–193, January 2014
How to Cite
Ferry, A., Stemper, J., Marinetti, A., Voituriez, A. and Guinchard, X. (2014), Thiophostone-Derived Brønsted Acids in the Organocatalyzed Transfer Hydrogenation of Quinolines: Influence of the P-Stereogenicity. Eur. J. Org. Chem., 2014: 188–193. doi: 10.1002/ejoc.201301253
- Issue published online: 18 DEC 2013
- Article first published online: 24 OCT 2013
- Manuscript Received: 20 AUG 2013
- Brønsted acids
A new approach to Brønsted acid organocatalysis is described and is based on the use of thiophosphonic acids possessing both a chiral backbone and a chiral phosphorus function. The influence of the phosphorus stereochemistry on the enantioselectivity proved to be crucial in the hydrogen transfer hydrogenation of 2-phenylquinoline with Hantzsch esters.