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Silver(I)-Mediated Dual Cleavage of C–C and C–O Bonds in the Reaction of Diarylmethylenecyclopropanes with Tetrahydrofuran: Synthesis of 4-(3-Halobut-3-enyloxy)butyl 2,2,2-Trifluoroacetate Derivatives



The reaction of methylenecyclopropanes (MCPs) with tetrahydrofuran (THF) proceed smoothly in the presence of AgOC(O)CF3 and electrophilic halogenation reagents to give the corresponding 4-(3-halobut-3-enyloxy)butyl 2,2,2-trifluoroacetate derivatives in moderate yields through dual cleavage of C–C and C–O bonds under mild conditions.