Pseudoanguillosporin A and B: Two New Isochromans Isolated from the Endophytic Fungus Pseudoanguillospora sp. (pages 1427–1434)
Ines Kock, Siegfried Draeger, Barbara Schulz, Brigitta Elsässer, Tibor Kurtán, Ágnes Kenéz, Sándor Antus, Gennaro Pescitelli, Piero Salvadori, John-Bryan Speakman, Joachim Rheinheimer and Karsten Krohn
Article first published online: 4 FEB 2009 | DOI: 10.1002/ejoc.200801083
The structure of two new bioactive isochromans, pseudoanguillosporin A (2a) and B (3), was determined by NMR spectroscopy and the absolute configuration by a combination of CD spectroscopy, TDDFT CD calculations, and Mosher's NMR method. The axial chirality of 1 was assigned by exciton analysis of its CD spectrum and confirmed by ZINDO CD calculations.