Synthesis of Cucurbituril Derivatives and Insights into Their Solubility in Water (pages 3857–3865)
Véronique Lewin, Julie Rivollier, Sylvie Coudert, David-Alexandre Buisson, Delphine Baumann, Bernard Rousseau, François-Xavier Legrand, Hana Kouřilová, Patrick Berthault, Jean-Pierre Dognon, Marie-Pierre Heck and Gaspard Huber
Article first published online: 26 APR 2013 | DOI: 10.1002/ejoc.201300229
New molecules derived from cucurbituril with either a propanediurea unit or cyclohexane moieties have been synthesized. Their solubility in pure water increased with the number of these nonclassical units. This can be explained in terms of changes in intermolecular C–H···O hydrogen bonding rather than in the molecular shape.