European Journal of Organic Chemistry

Cover image for Vol. 2013 Issue 20

July 2013

Volume 2013, Issue 20

Pages 4179–4449

  1. Cover Picture

    1. Top of page
    2. Cover Picture
    3. Graphical Abstract
    4. News
    5. Microreview
    6. Short Communications
    7. Full Papers
    1. You have free access to this content
      Following the Lead from Nature: Divergent Pathways in Natural Product Synthesis and Diversity-Oriented Synthesis (Eur. J. Org. Chem. 20/2013)

      Christelle Serba and Nicolas Winssinger

      Version of Record online: 3 JUL 2013 | DOI: 10.1002/ejoc.201390055

      Thumbnail image of graphical abstract

      The cover picture shows illustrates recent efforts in chemical synthesis to design strategic pluripotent intermediates that can be engaged in divergent reaction pathways. The same logic can be found in biosynthetic pathways and offers a powerful scheme to access a broad molecular diversity space. Synthetically, great progress has been made in the development and use of powerful complexity-generating reactions and cascade reactions. These strategies are increasingly used in the chemical synthesis of natural products and yield synthetic schemes that afford a family of natural products rather than a single target. As illustrated graphically, one strategy that parallels sesquiterpene biosynthesis is to start from an acyclic linear precursor that is cyclized, which yields distinct scaffolds upon treatment with different reagents. Details are presented in the Microreview by C. Serba and N. Winssinger on page 4195 ff..

  2. Graphical Abstract

    1. Top of page
    2. Cover Picture
    3. Graphical Abstract
    4. News
    5. Microreview
    6. Short Communications
    7. Full Papers
  3. News

    1. Top of page
    2. Cover Picture
    3. Graphical Abstract
    4. News
    5. Microreview
    6. Short Communications
    7. Full Papers
  4. Microreview

    1. Top of page
    2. Cover Picture
    3. Graphical Abstract
    4. News
    5. Microreview
    6. Short Communications
    7. Full Papers
    1. Divergent Synthesis

      Following the Lead from Nature: Divergent Pathways in Natural Product Synthesis and Diversity-Oriented Synthesis (pages 4195–4214)

      Christelle Serba and Nicolas Winssinger

      Version of Record online: 16 MAY 2013 | DOI: 10.1002/ejoc.201300201

      Thumbnail image of graphical abstract

      Strategically divergent: Designing synthetic pathways from pluripotent intermediates. Getting more molecules for your carbon.

  5. Short Communications

    1. Top of page
    2. Cover Picture
    3. Graphical Abstract
    4. News
    5. Microreview
    6. Short Communications
    7. Full Papers
    1. Natural Products

      Towards the Total Synthesis of Marineosin A: Construction of the Macrocyclic Pyrrole and an Advanced, Functionalized Spiroaminal Model (pages 4215–4218)

      Leslie N. Aldrich, Cynthia B. Berry, Brittney S. Bates, Leah C. Konkol, Miranda So and Craig W. Lindsley

      Version of Record online: 4 JUN 2013 | DOI: 10.1002/ejoc.201300643

      Thumbnail image of graphical abstract

      Closing in on Marineosin A: Herein, we describe the enantioselective construction of the 12-membered macrocyclic pyrrole core of marineosin A and a highly functionalized spiroaminal from (S)-propylene oxide as a chiral pool starting material. TBDPS = tert-butyldiphenylsilyl, Piv = pivalate.

    2. Ring-Opening Reactions

      Palladium-Catalyzed Ring-Opening Alkynylation of Cyclopropenones (pages 4219–4222)

      Takanori Matsuda and Yusuke Sakurai

      Version of Record online: 23 MAY 2013 | DOI: 10.1002/ejoc.201300220

      Thumbnail image of graphical abstract

      The ring-opening alkynylation of cyclopropenones with terminal alkynes is catalyzed by palladium–N-heterocyclic carbene (NHC) complexes to provide alkenyl alkynyl ketones. In contrast, [3+2] annulation to give cyclopentenones occurs if secondary propargylic esters bearing an aryl or alkenyl substituent are used.

    3. Biocatalysis

      Chymotrypsin-Catalyzed Peptide Synthesis in Deep Eutectic Solvents (pages 4223–4228)

      Zaira Maugeri, Walter Leitner and Pablo Domínguez de María

      Version of Record online: 4 JUN 2013 | DOI: 10.1002/ejoc.201300448

      Thumbnail image of graphical abstract

      Tackling challenging substrates: Deep eutectic solvents (DESs) may be used in enzymatic peptide synthesis to dissolve substrates with different polarities. This method provides a route to novel entries for sustainable chemistry.

    4. Oxidative Amidation

      Selenium-Promoted Intramolecular Oxidative Amidation of 2-(Arylamino)acetophenones for the Synthesis of N-Arylisatins (pages 4229–4232)

      Yong Liu, Hui Chen, Xiong Hu, Wang Zhou and Guo-Jun Deng

      Version of Record online: 5 JUN 2013 | DOI: 10.1002/ejoc.201300477

      Thumbnail image of graphical abstract

      An efficient method for the synthesis of N-arylisatins from 2-(arylamino)acetophenones by using SeO2 as an oxidant under transition-metal-free conditions is described. The reaction proceeds smoothly in dioxane at 80 °C and gives the corresponding products in high yields. The reaction tolerates a wide range of functionalities.

    5. Tröger's Base P Ligands

      Tröger's Base Derived Phosphanes for ­Suzuki–Miyaura and Buchwald–Hartwig Cross-Coupling Reactions (pages 4233–4237)

      Raul Pereira and Ján Cvengroš

      Version of Record online: 5 JUN 2013 | DOI: 10.1002/ejoc.201300519

      Thumbnail image of graphical abstract

      Easily accessible bisphosphane ligands based on the 2,8-substituted Tröger's base scaffold are synthesized and effectively applied in palladium-catalyzed C–C and C–N bond-forming reactions of aryl chlorides and bromides.

    6. Sulfur Ylides in Synthesis

      Improvement in the One-Carbon Chain Extension of Esters with Dimethylsulf­oxonium Methylide (pages 4238–4241)

      Hoa Luong, Eduard Luss-Lusis, Gerald J. Tanoury and William A. Nugent

      Version of Record online: 5 JUN 2013 | DOI: 10.1002/ejoc.201300526

      Thumbnail image of graphical abstract

      Taking on water: A recent report that reaction of esters with dimethylsulfoxonium methylide actually produces carboxylate salts rather than the expected chain-extended sulfur ylides has been investigated and traced to the effect of adventitious water. This insight has allowed an improvement in the chain-extension reaction.

    7. Natural Products

      Concise Total Synthesis of Hydrazidomycin A, a Rare Hydrazide Metabolite of Streptomyces atratus (pages 4242–4244)

      Florian Meyer, Nico Ueberschaar and Christian Hertweck

      Version of Record online: 6 JUN 2013 | DOI: 10.1002/ejoc.201300532

      Thumbnail image of graphical abstract

      The naturally occurring hydrazine derivative hydrazidomycin A, an antiproliferative metabolite of Streptomyces atratus, was synthesized for the first time. The versatile reaction sequence involves a ruthenium-catalyzed Z-selective N-alkenylation.

    8. Phosphonation

      Silver-Catalyzed Highly Regioselective Phosphonation of Arenes Bearing Electron-Withdrawing Groups (pages 4245–4248)

      Xuerong Mao, Xiao Ma, Shuwei Zhang, Hongwen Hu, Chengjian Zhu and Yixiang Cheng

      Version of Record online: 5 JUN 2013 | DOI: 10.1002/ejoc.201300545

      Thumbnail image of graphical abstract

      A highly regioselective phosphonation reaction has been developed by using N,N-dialkyl-substituted amides, N,N-dialkylsulfonamides, and nitro groups as directing groups (DGs); Ag2SO4 as a catalyst; and K2S2O8 as a benign oxidant under mild reaction conditions. This method has a broad scope and offers facile construction of C–P bonds.

    9. Organofluorine Compounds

      A New Life for an Old Reagent: Fluoroalkyl Amino Reagents as Efficient Tools for the Synthesis of Diversely Fluorinated Pyrazoles (pages 4249–4253)

      Sergiy Pazenok, Florence Giornal, Grégory Landelle, Norbert Lui, Jean-Pierre Vors and Frédéric R. Leroux

      Version of Record online: 28 MAY 2013 | DOI: 10.1002/ejoc.201300561

      Thumbnail image of graphical abstract

      FAR out! Unsymmetrical 3,5-bis(fluoroalkyl)pyrazoles are regioselectively synthesized by a straightforward one-pot sequence. Treatment of fluorinated β-keto esters with (tetrafluoroethyl)dimethylamine (TFEDMA) as a practical CF2H transfer reagent and subsequent cyclocondensation with hydrazine derivatives affords 3-(difluoromethyl)-5-(fluoroalkyl)pyrazoles as single isomers. Rf = fluorinated alkyl group.

  6. Full Papers

    1. Top of page
    2. Cover Picture
    3. Graphical Abstract
    4. News
    5. Microreview
    6. Short Communications
    7. Full Papers
    1. Carbanions

      Quantification of the Nucleophilic Reactivities of Ethyl Arylacetate Anions (pages 4255–4261)

      Francisco Corral-Bautista and Herbert Mayr

      Version of Record online: 24 MAY 2013 | DOI: 10.1002/ejoc.201300265

      Thumbnail image of graphical abstract

      The kinetics of the reactions of the anions of ethyl arylacetates with quinone methides and diethyl benzylidenemalonates were investigated in DMSO solution. The resulting rate constants follow the linear free-energy relationship lg k2 = sN(N + E), which allowed us to derive their reactivity parameters N and sN.

    2. Two-Photon Chromophores

      Synthesis and Two-Photon Absorption Properties of Symmetrical Chromophores Derived from 2,3,5-Trisubstituted Quinoxaline Units (pages 4262–4269)

      Tzu-Chau Lin, Wei Chien, Che-Yu Liu, Ming-Yu Tsai and Yu-Jheng Huang

      Version of Record online: 3 JUN 2013 | DOI: 10.1002/ejoc.201300345

      Thumbnail image of graphical abstract

      A multipolar chromophore set composed of three analogues with various central π bridges and functionalized quinoxaline moieties as the major building units possesses strong and widely dispersed molecular two-photon absorption. The potential of these compounds as effective optical power limiters and stabilizers is also demonstrated.

    3. Functionalized BODIPY Derivatives

      BODIPY Dyes Functionalized with Pendant Cyclic and Acyclic Polyamines (pages 4270–4279)

      Yulia A. Volkova, Bertrand Brizet, Pierre D. Harvey, Alexey D. Averin, Christine Goze and Franck Denat

      Version of Record online: 23 MAY 2013 | DOI: 10.1002/ejoc.201300414

      Thumbnail image of graphical abstract

      The nucleophilic substitution of a 3,5-dichloro-BODIPY derivative with several polyazamacrocycles was investigated. By controlling the BODIPY/macrocycle ratio, some monomeric and dimeric species could be obtained. The photophysical properties of the compounds were studied as was the influence of different cations for one system.

    4. Tandem Reactions

      Synthesis of 6H-Isoindolo[2,1-a]indol-6-ones Through Wittig Reaction and Tandem Reductive Cyclization–Lactamization (pages 4280–4284)

      Hari K. Kadam and Santosh G. Tilve

      Version of Record online: 23 MAY 2013 | DOI: 10.1002/ejoc.201300047

      Thumbnail image of graphical abstract

      A two-step route involving Wittig reaction followed by tandem reductive cyclization–lactamization is presented for the synthesis of 6H-Isoindolo[2,1-a]indol-6-ones.

    5. Halothiophenes

      Synthetic Access to Hydrogen and Halogen Derivatives of 3-Amino-4-nitrothiophenes (pages 4285–4293)

      Eva-Janina Vogt, Viktor A. Zapol'skii, Eva Nutz and Dieter E. Kaufmann

      Version of Record online: 21 MAY 2013 | DOI: 10.1002/ejoc.201300006

      Thumbnail image of graphical abstract

      Starting from per-substituted 3-amino-4-nitrothiophenes with a 2-chloro- and a 5-vinylsulfanyl substituent the formation of vinyl-S-oxides and subsequent substitution against nucleophiles is reported. Additionally, dehalogenation of the formed halothiophenes is possible with three different methods, which lead to selective dehalogenation at the 2, 5 or 2 and 5 position.

    6. Atropisomeric Ligands

      Bile Acid Derived Tropos Vaulted Bi­naphth­ylphosphites: Synthesis, Stereo­chemical Characterization and Complexation to Rhodium (pages 4294–4302)

      Varsha R. Jumde and Anna Iuliano

      Version of Record online: 21 MAY 2013 | DOI: 10.1002/ejoc.201300024

      Thumbnail image of graphical abstract

      Chirality transfer from the cholestanic backbone of bile acid derivatives to the flexible 2,2′-binaphthyl-1,1′-diylphosphite moiety was obtained in the synthesis of three different phosphite ligands.

    7. Multicomponent Reactions

      Efficient Consecutive Four-Component Synthesis of 5-Acylpyrid-2-ones Initiated by Copper-Free Alkynylation (pages 4303–4310)

      Jan Nordmann, Natascha Breuer and Thomas J. J. Müller

      Version of Record online: 29 MAY 2013 | DOI: 10.1002/ejoc.201300235

      Thumbnail image of graphical abstract

      The Pd/cataCXium® ABn catalyst system considerably facilitates the one-pot, consecutive, four-component synthesis of 5-acylpyrid-2-ones with a high degree of diversity and the use of almost equimolar stoichiometric amounts of all four compounds.

    8. Glycerolipids

      Optically Active Monoacylglycerols: Synthesis and Assessment of Purity (pages 4311–4318)

      Chao-Yuan Chen, Wei-Bo Han, Hui-Jun Chen, Yikang Wu and Po Gao

      Version of Record online: 21 MAY 2013 | DOI: 10.1002/ejoc.201300247

      Thumbnail image of graphical abstract

      Because of facile acyl migrations, the synthesis of enantiopure 1(or 3)-acyl-sn-glycerols is much more difficult than their seemingly very simple structures may imply. Even assessment of their optical purity is a difficult task because of the lack of a feasible means of analysis. Now, new findings have changed everything.

    9. 1,2-Diamines

      Scalable Synthesis of Enantiomerically Pure cis-1,2-Cyclohexanediamine Derivatives and Conformationally Rigid 7-Aza­bi­cyclo[2.2.1]heptan-2-amines (pages 4319–4324)

      Ganesh Pandey, Debasis Dey and Rushil Fernandes

      Version of Record online: 16 MAY 2013 | DOI: 10.1002/ejoc.201300253

      Thumbnail image of graphical abstract

      The 7-azabicyclo[2.2.1]heptane skeleton was exploited to achieve a new approach to the syntheses of enantiomerically pure cis-1,2-cyclohexanediamine derivatives and conformationally rigid 7-azabicyclo[2.2.1]heptan-2-amines. This was achieved on a multigram scale without producing the undesired diastereomers.

    10. Amide Formation

      Amide Formation Using In Situ Activation of Carboxylic Acids with [Et2NSF2]BF4 (pages 4325–4331)

      Olivier Mahé, Justine Desroches and Jean-François Paquin

      Version of Record online: 23 MAY 2013 | DOI: 10.1002/ejoc.201300289

      Thumbnail image of graphical abstract

      The formation of amides through the in situ activation of carboxylic acids with [Et2NSF2]BF4 is presented. A wide range of carboxylic acids and amines were used to produce the corresponding amides in up to 99 % yield. The reaction with hindered amines was also possible under slightly modified conditions. An enantiopure carboxylic acid and amine were shown to react without racemization.

    11. Total Synthesis

      A Concise and Efficient Total Synthesis of Oleocanthal (pages 4332–4336)

      Matteo Valli, Elena Giulia Peviani, Alessio Porta, Alessandro D'Alfonso, Giuseppe Zanoni and Giovanni Vidari

      Version of Record online: 23 MAY 2013 | DOI: 10.1002/ejoc.201300324

      Thumbnail image of graphical abstract

      Oleocanthal, a component of extra virgin olive oil, possesses anti-inflammatory activity and inhibits the formation of neurofibrillary tangles. In this paper, we have achieved the shortest synthesis of (±)-oleocanthal reported so far from easily available starting materials. Chiral chromatographic resolution of the mixture provided both enantiomers for biological studies.

    12. Asymmetric Catalysis

      Tandem Iminium/Copper Catalysis: Highly Enantioselective Synthesis of α,β-Disubstituted Aldehydes (pages 4337–4344)

      Ju-Hye Kim, Eun-Jin Park, Hwa-Jung Lee, Xuan-Huong Ho, Hyo-Sang Yoon, Pilsoo Kim, Hoseop Yun and Hye-Young Jang

      Version of Record online: 27 MAY 2013 | DOI: 10.1002/ejoc.201300333

      Thumbnail image of graphical abstract

      The combination of a chiral amine catalyst and a copper complex allows the synthesis of α,β-disubstituted aldehydes from unsaturated aldehydes with good yields and excellent stereoselectivity.

    13. Biaryl Compounds

      An Aerobic and Very Fast Pd/C-Catalyzed Ligand-Free and Aqueous Suzuki Reaction Under Mild Conditions (pages 4345–4350)

      Chun Liu, Xiaofeng Rao, Yixia Zhang, Xinmin Li, Jieshan Qiu and Zilin Jin

      Version of Record online: 17 JUN 2013 | DOI: 10.1002/ejoc.201300334

      Thumbnail image of graphical abstract

      A very simple, general, and highly efficient Pd/C-catalyzed Suzuki reaction under ligand-free and aerobic conditions was developed. This protocol could be applied to the synthesis of fluorinated liquid-crystalline compounds. The Pd/C catalyst could be recycled at least ten times without significant loss of catalytic activity.

    14. Birch Reduction

      The Reactivity of Arylphosphorus Acid Amides Under Birch Reduction Conditions (pages 4351–4371)

      Marek Stankevič, Adam Włodarczyk and Damian Nieckarz

      Version of Record online: 24 MAY 2013 | DOI: 10.1002/ejoc.201300344

      Thumbnail image of graphical abstract

      Treatment of arylphosphorus acid amides with alkali metal solutions in liquid ammonia results in dearomatisation of the arene fragments and formation of (cyclohexa-1,4-dien-3-yl)phosphorus acid amides. Diarylphosphinic amides tend to undergo Birch reduction of two arene fragments to form bis(cyclohexadienyl)phosphinic amides.

    15. Peptide Modification

      Straightforward Approach to Ferrocenyl Amino Acids and Peptides by Allylic Alk­ylation (pages 4372–4378)

      Jan Gorges, Angelika Ullrich and Uli Kazmaier

      Version of Record online: 3 JUN 2013 | DOI: 10.1002/ejoc.201300346

      Thumbnail image of graphical abstract

      Peptides containing a ferrocenyl side-chain can easily be obtained in a highly regio- as well as stereoselective fashion by palladium-catalyzed allylic alkylation using ferrocenylallyl carbonates.

    16. The Bielschowskysin Core

      Photochemical and Thermal [2 + 2] Cycloaddition to Generate the Bicyclo[3.2.0]­hept­ane Core of Bielschowskysin (pages 4379–4398)

      Jean-Baptiste Farcet, Martin Himmelbauer and Johann Mulzer

      Version of Record online: 7 JUN 2013 | DOI: 10.1002/ejoc.201300382

      Thumbnail image of graphical abstract

      Various photocycloaddition precursors have been designed to study both biomimetic and non-biomimetic [2 + 2] cycloadditions to form the bicyclo[3.2.0]heptane core of the marine diterpenoid bielschowskysin. Additionally, an optimized thermal approach to aldehyde (–)-55 is described.

    17. Aza-Claisen Rearrangements

      1,2-Asymmetric Induction in Diastereo­selective Zwitterionic Aza-Claisen Rearrangements: Key Steps in Optically Active Alkaloid Synthesis (pages 4399–4404)

      Carolin Heescher, Dieter Schollmeyer and Udo Nubbemeyer

      Version of Record online: 23 MAY 2013 | DOI: 10.1002/ejoc.201300389

      Thumbnail image of graphical abstract

      The zwitterionic aza-Claisen rearrangement of optially active N-allylpyrrolidines and α-phenoxyacetyl fluorides proceeds with complete internal and complete 1,2-asymmetric induction to generate a new C–C bond adjacent to a chiral C-N-Boc functionality. The resulting γ,δ-unsaturated amides serve as key chiral intermediates for the total synthesis of pyrrolizidine alkaloid derivatives.

    18. Ynol Ethers

      Synthesis of Alkyl-Ynol-Ethers by “Anti-Michael Addition” of Metal Alkoxides to β-Substituted Alkynylsulfones (pages 4405–4409)

      Leyre Marzo, Alejandro Parra, María Frías, José Alemán and José Luis García Ruano

      Version of Record online: 21 MAY 2013 | DOI: 10.1002/ejoc.201300395

      Thumbnail image of graphical abstract

      Ynol ethers can be directly obtained under mild conditions by reaction of KOR with β-substituted 2(-p-tolylsulfonyl)acetylenes. Only arylacetylenes (with KOtBu) and TIPS-acetylenes provide good yields of alkyl ethynyl ethers

    19. Medium Ring Synthesis

      Diastereoselective Synthesis of Isoindole-Fused Diazacyclooctaindenones from Spiro­chromenes through Domino Reactions with Aliphatic 1,2-Diamines (pages 4410–4417)

      Sudipta Pathak and Animesh Pramanik

      Version of Record online: 23 MAY 2013 | DOI: 10.1002/ejoc.201300096

      Thumbnail image of graphical abstract

      A diastereoselective synthesis of isoindole-fused diazacyclooctaindenone derivatives has been accomplished through tandem ring-opening and ring-closing of spirochromene derivatives triggered by different aliphatic 1,2-diamines.

    20. Unsaturated Diesters

      Synthesis of Unsaturated Diesters of Primary, Secondary and Tertiary Diols Derived from Dimethyl (+)-Tartrate and Galactaric­ Acid (pages 4418–4426)

      Jimena Scoccia, Darío C. Gerbino, Victor F. Terraza, Adriana E. Zúñiga and Julio C. Podestá

      Version of Record online: 23 MAY 2013 | DOI: 10.1002/ejoc.201300130

      Thumbnail image of graphical abstract

      The synthesis of symmetrical unsaturated diesters of types AC, obtained from primary, secondary, and tertiary diols derived of dimethyl (+)-tartrate and galactaric acid, is reported. Of the four methods tested, the best was the reaction between the diols and unsaturated acid chlorides in the presence of nBuLi in diethyl ether at –50 °C; this approach affords the diesters in an average yield of 78 %.

    21. Natural Product Synthesis

      Asymmetric Formal Synthesis of (–)-Swainsonine by a Highly Regioselective and Diastereoselective Allylic Amination Using Chlorosulfonyl Isocyanate (pages 4427–4433)

      Qing Ri Li, Guang Ri Dong, Sook Jin Park, Yong Rae Hong, In Su Kim and Young Hoon Jung

      Version of Record online: 31 MAY 2013 | DOI: 10.1002/ejoc.201300308

      Thumbnail image of graphical abstract

      A concise asymmetric formal synthesis of (–)-swainsonine from readily available D-erythronolactone is described. The key steps include a highly diastereoselective amination of a chiral benzylic ether, which occurs with the retention of stereochemistry using chlorosulfonyl isocyanate, and a palladium-catalyzed decarboxylative N-allylation of an allyl carbamate.

    22. Phosphane Catalysis

      A Highly Regio- and Diastereoselective Phosphane-Catalyzed [3+2] Annulation of Morita–Baylis–Hillman Carbonates with Cyclic N-Acyl Ketimines (pages 4434–4442)

      Li-Jun Yang, Hua Cai, Jing Nie and Jun-An Ma

      Version of Record online: 7 JUN 2013 | DOI: 10.1002/ejoc.201300342

      Thumbnail image of graphical abstract

      In the presence of the catalyst PBu3, Morita–Baylis–Hillman (MBH) carbonates and cyclic N-acyl-substituted ketimines underwent a [3+2] annulation to afford N-fused tricyclic compounds in 90–99 % yields and >99:1 dr. The addition of a chiral nucleophilic phosphane to this reaction afforded the annulation product in high yield and diastereoselectivity with moderate enantioselectivity.

    23. Cavitand Ligand Design

      Subtle Steric Effects in Nickel-Catalysed Kumada–Tamao–Corriu Cross-Coupling Using Resorcinarenyl-Imidazolium Salts (pages 4443–4449)

      Neslihan Şahin, David Sémeril, Eric Brenner, Dominique Matt, İsmail Özdemir, Cemal Kaya and Loïc Toupet

      Version of Record online: 4 JUN 2013 | DOI: 10.1002/ejoc.201300347

      Thumbnail image of graphical abstract

      Highly efficient catalysts for cross-coupling between aryl halides and aryl Grignard reagents were obtained by mixing appropriate nickel complexes with imidazolium salts based on resorcinarene cavitands. Their high activity was attributed to steric effects involving flexible side chains grafted at two methine carbon atoms.

SEARCH

SEARCH BY CITATION