Multigram Synthesis of Fluoroalkyl-Substituted Pyrazole-4-carboxylic Acids (pages 886–891)
Rustam T. Iminov, Alexander V. Mashkov, Ivan I. Vyzir, Bohdan A. Chalyk, Anton V. Tverdokhlebov, Pavel K. Mykhailiuk, Ludmila N. Babichenko, Andrey A. Tolmachev, Yulian M. Volovenko, Angelina Biitseva, Oleg V. Shishkin and Svetlana V. Shishkina
Article first published online: 22 DEC 2014 | DOI: 10.1002/ejoc.201403295
Fluorinated pyrazolecarboxylic acids ― potential building blocks for agrochemical applications ― have been prepared on a multigram scale. The easy separation of the isomeric mixture of esters was the key feature of the synthesis.