In the present study a daily event-recording method, the DIRO (Daily Interaction Record in Organizations), was employed for assessing social interactions, stressful events and negative affect at work. Forty-one secretaries filled out the records during the course of a week. This made it possible to consider both between-and within-subject effects of social interactions. The results showed that the social interactions of secretaries were characterized by three dimensions: intimate support, instrumental support and rewarding companionship. These three dimensions appeared to have different relationships with occupational stress. Instrumental support seemed to play the most important role in the work of secretaries, whereas rewarding companionship played no role at all in alleviating occupational stress. In the discussion some explanations are offered for this unexpected result.