Feature Article

Potential-Controlled Chromatography of Short-Chain Carboxylic Acids

  1. M. W. Knizia1,
  2. K. Vuorilehto2,
  3. J. Schrader3,
  4. D. Sell3

Article first published online: 27 JAN 2003

DOI: 10.1002/elan.200390004

Issue

Electroanalysis

Electroanalysis

Volume 15, Issue 1, pages 49–54, January 2003

Additional Information

How to Cite

Knizia, M., Vuorilehto, K., Schrader, J. and Sell, D. (2003), Potential-Controlled Chromatography of Short-Chain Carboxylic Acids. Electroanalysis, 15: 49–54. doi: 10.1002/elan.200390004

Author Information

  1. 1

    Merck KGaA, Feurigstr. 38, 10827 Berlin, Germany

  2. 2

    Helsinki University of Technology, Laboratory of Corrosion and Material Chemistry, Vuorimiehentie 2, 02150 Espoo, Finland

  3. 3

    Karl-Winnacker-Institut der DECHEMA e. V., Theodor-Heuss-Allee 25, 60486 Frankfurt am Main, Germany

Publication History

  1. Issue published online: 27 JAN 2003
  2. Article first published online: 27 JAN 2003
  3. Manuscript Accepted: 12 APR 2002
  4. Manuscript Received: 28 SEP 2001

SEARCH

SEARCH BY CITATION

ARTICLE TOOLS

Get PDF (150K)

Keywords:

  • Liquid chromatography;
  • Electrically conductive stationary phase;
  • Electrosorption;
  • Potential-controlled retention

Abstract

A chromatographic column was constructed which could be operated with an electrically conductive stationary phase of graphite particles. This column allowed chromatographic experiments at variable electric potentials of the column material. The chromatographic behavior of selected carboxylic acids was significantly influenced at positive column potentials. An equimolar mixture of three different carboxylic acids were separated at a potential of +600 mV (versus. Ag/AgCl). Surprisingly, the stereoisomers maleic and fumaric acid, which are identical in molecular mass and charge, could also be separated. Further improvements to the chromatographic performance were achieved by applying potential drops and linear potential gradients.

Get PDF (150K)