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Section A: Enzyme-Based Biofuel Cells
Protein Engineering – An Option for Enzymatic Biofuel Cell Design
Article first published online: 22 FEB 2010
DOI: 10.1002/elan.200980017
Copyright © 2010 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
1521-4109/asset/cover.gif?v=1&s=209b447dcf920ba3fb44f2b08a87a6b586320422 "Electroanalysis")
Additional Information
How to Cite
Güven, G., Prodanovic, R. and Schwaneberg, U. (2010), Protein Engineering – An Option for Enzymatic Biofuel Cell Design. Electroanalysis, 22: 765–775. doi: 10.1002/elan.200980017
Publication History
- Issue published online: 1 APR 2010
- Article first published online: 22 FEB 2010
- Manuscript Accepted: 30 OCT 2009
- Manuscript Received: 15 JUN 2008
- Abstract
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Keywords:
- Biofuel cells;
- Biocatalysis;
- Protein engineering;
- Rational design;
- Directed evolution;
- Fuel cells
Abstract
This review summarizes and discusses from a protein engineering point of view strategies to improve performances of biocatalysts in enzymatic biofuel cells. Emphasis will be given on biocatalysts employed in biofuel cells and protein engineering principles for achieving an efficient electrical communication between electrode and biocatalyst(s). Biocatalyst engineering by Rational Design and Directed Evolution offers opportunities to redesign and to improve biocatalysts for biofuel cell applications instead of accepting insufficient biocatalyst properties as unalterable limitations in the development of biofuel cells.