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Surface-Imprinting Sensor Based on Carbon Nanotubes/Graphene Composite for Determination of Bovine Serum Albumin

Authors

  • Hong-Jun Chen,

    1. Key laboratory of Hunan Forest Products and Chemical Industry Engineering, Jishou University, Hunan 427000, P. R. China tel: +86-743-8563911; fax: +86-743-8563911
    2. College of Chemistry and Chemical Engineering, Jishou University, Hunan 416000, P. R. China
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  • Zhao-Hui Zhang,

    Corresponding author
    1. Key laboratory of Hunan Forest Products and Chemical Industry Engineering, Jishou University, Hunan 427000, P. R. China tel: +86-743-8563911; fax: +86-743-8563911
    2. College of Chemistry and Chemical Engineering, Jishou University, Hunan 416000, P. R. China
    • Key laboratory of Hunan Forest Products and Chemical Industry Engineering, Jishou University, Hunan 427000, P. R. China tel: +86-743-8563911; fax: +86-743-8563911
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  • Duo Xie,

    1. College of Chemistry and Chemical Engineering, Jishou University, Hunan 416000, P. R. China
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  • Rong Cai,

    1. College of Chemistry and Chemical Engineering, Jishou University, Hunan 416000, P. R. China
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  • Xing Chen,

    1. College of Chemistry and Chemical Engineering, Jishou University, Hunan 416000, P. R. China
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  • Yu-Nan Liu,

    1. College of Chemistry and Chemical Engineering, Jishou University, Hunan 416000, P. R. China
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  • Shou-Zhuo Yao

    1. State Key Laboratory of Chemo/Biosensing and Chemometrics, Hunan 410082, P. R. China
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Abstract

A novel molecularly imprinted sensor was firstly prepared based on a carbon nanotubes/graphene composite modified carbon electrode (MIPs/CNT/GP/CE) for the selective determination of bovine serum albumin. The molecularly imprinted sensor was tested by differential pulse voltammetry (DPV) to investigate the relationship between the response current and bovine serum albumin concentration. The results showed that a wide linear range (1.0×10−4 to 1.0×10−10 g mL−1) for the detection of bovine serum albumin with a low detection limit of 6.2×10−11 g mL−1 for S/N=3 was obtained. The novel imprinted sensor exhibited high selectivity, sensitivity, and reproducibility, which provided an applicable way for sensor development.

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