An Immunosensor for Ultrasensitive Detection of 1-Pyrenebutyric Acid with Enhanced Electrochemical Performance Based on a Graphene-Ionic Liquid Doped Chitosan Film Modified Glassy Carbon Electrode

Authors

  • Xu Shuangjie,

    1. Department of environment science and engineer, The university of Donghua, Postal Code, 201620, Shanghai, P. R. China
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  • Xu He,

    Corresponding author
    1. Department of environment science and engineer, The university of Donghua, Postal Code, 201620, Shanghai, P. R. China
    • Department of environment science and engineer, The university of Donghua, Postal Code, 201620, Shanghai, P. R. China
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  • Liu Jianshe

    Corresponding author
    1. Department of environment science and engineer, The university of Donghua, Postal Code, 201620, Shanghai, P. R. China
    • Department of environment science and engineer, The university of Donghua, Postal Code, 201620, Shanghai, P. R. China
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Abstract

This paper describes a highly sensitive and label-free electrochemical immunosensor for the detection of 1-pyrenebutyric acid (PBA) which is based on a graphene (GS), chitosan (CS), and ionic liquid (IL) composite modified glassy carbon electrode (GS-CS-IL/GCE). The modification process was monitored by transmission electron microscopy (TEM) and cyclic voltammetry (CV). Due to the synergistic effects of GS, CS, and IL, the biosensor exhibits excellent selectivity to PBA. The current response of the proposed immunosensor decreases linearly at two concentration ranges from 0.01 to 5 and from 5 to 150 ng mL−1 with a detection limit of 0.01 ng mL−1.

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