Modification of Poly- and Oligosaccharides with Os(VI)pyridine. Voltammetry of the Os(VI) Adducts Obtained by Ligand Exchange

Authors

  • Mojmír Trefulka,

    1. Institute of Biophysics, Academy of Sciences of the Czech Republic v.v.i., Kralovopolska 135, 612 65 Brno, Czech Republic
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  • Emil Paleček

    Corresponding author
    1. Institute of Biophysics, Academy of Sciences of the Czech Republic v.v.i., Kralovopolska 135, 612 65 Brno, Czech Republic
    • Institute of Biophysics, Academy of Sciences of the Czech Republic v.v.i., Kralovopolska 135, 612 65 Brno, Czech Republic
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Abstract

Polysaccharides and oligosaccharides were modified with Os(VI)pyridine complex followed by ligand exchange with different ligands such as 2,2′-bipyridine or N,N,N′,N′-tetramethylethylenediamine. The time of the modification was much shorter (taking about 15 min) then direct modification with the given Os(VI) complex. The resulting saccharide adducts were analyzed by voltammetric methods at carbon and mercury electrodes. The results showed that the proposed technique gives promise for a new approach to analysis of glycoproteins.

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