Article

The grammatical rule for all DNA: Junk and coding sequences

  1. Dr. Susumu Ohno1,*,
  2. Tetsuya Yomo2

Article first published online: 13 APR 2005

DOI: 10.1002/elps.1150120203

Issue

ELECTROPHORESIS

ELECTROPHORESIS

Volume 12, Issue 2-3, pages 103–108, 1991

Additional Information

How to Cite

Ohno, S. and Yomo, T. (1991), The grammatical rule for all DNA: Junk and coding sequences. ELECTROPHORESIS, 12: 103–108. doi: 10.1002/elps.1150120203

Author Information

  1. 1

    Beckman Research Institute of the City of Hope, Department of Theoretical Biology, Duarte, CA

  2. 2

    Department of Fermentation Technology, Faculty of Engineering, Osaka University, Osaka

*Department of Theoretical Biology, Beckman Research Institute of the City of Hope, 1450 E. Duarte Road, Duarte, CA 91010-0269, USA

Publication History

  1. Issue published online: 13 APR 2005
  2. Article first published online: 13 APR 2005
  3. Manuscript Received: 15 JUN 1990

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Abstract

Selfish DNA, coding sequences, and junk DNA in the genome are no stranger to each other; rather, they represent three phases in the life cycle of DNA. Accordingly, they all obey the same grammatical rule of TG/CA/CT excess and CG/TA deficiency. On the one hand, it is this very rule which keeps isoelectric points of most proteins near the neutral range. On the other hand, this rule creates numerous palindromes, thus maintaining symmetry between complementary strands. Many of these palindromes encode identical oligopeptides on both strands.

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