Review

Capillary electrophoresis and mass spectrometry for screening of metabolic disorders in newborns

  1. Petr Šenk1,
  2. Libor Kozák2,
  3. František Foret1,*

Article first published online: 2 JUN 2004

DOI: 10.1002/elps.200405853

Issue

ELECTROPHORESIS

ELECTROPHORESIS

Special Issue: Paper Symposium CAPILLARY ELECTROPHORESIS IN CLINICAL AND FORENSIC ANALYSIS

Volume 25, Issue 10-11, pages 1447–1456, No. 10-11 June 2004

Additional Information

How to Cite

Šenk, P., Kozák, L. and Foret, F. (2004), Capillary electrophoresis and mass spectrometry for screening of metabolic disorders in newborns. ELECTROPHORESIS, 25: 1447–1456. doi: 10.1002/elps.200405853

Author Information

  1. 1

    Institute of Analytical Chemistry

  2. 2

    Center of Molecular Biology and Gene Therapy, University Hospital Brno, Brno, Czech Republic

*Institute of Analytical Chemistry, Veveří 97, CZ-61142 Brno, Czech Republic Fax: +42-05-4121-2113

Publication History

  1. Issue published online: 2 JUN 2004
  2. Article first published online: 2 JUN 2004
  3. Manuscript Received: 9 JAN 2004

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Keywords:

  • Capillary electrophoresis;
  • Mass spectrometry;
  • Metabolic disorders in newborns;
  • Review

Abstract

Clinical analyses always represent a challenge for the sensitivity and selectivity of the analytical techniques. Of the most critical are the techniques required for the quick determination of the disease state and application of the proper treatment in newborns. This short critical review overviews the present state of the art of the use of mass spectrometry and capillary electrophoresis for screening of metabolic disorders in newborns.

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