CE and CEC

Recent advances in enhancing the sensitivity of electrophoresis and electrochromatography in capillaries and microchips (2006–2008)

  1. Michael C. Breadmore*,
  2. Jonathan R. E. Thabano,
  3. Mohamed Dawod,
  4. Artaches A. Kazarian,
  5. Joselito P. Quirino,
  6. Rosanne M. Guijt

Article first published online: 20 JAN 2009

DOI: 10.1002/elps.200800435

Issue

ELECTROPHORESIS

ELECTROPHORESIS

Special Issue: CE AND CEC REVIEWS

Volume 30, Issue 1, pages 230–248, January 2009

Additional Information

How to Cite

Breadmore, M. C., Thabano, J. R. E., Dawod, M., Kazarian, A. A., Quirino, J. P. and Guijt, R. M. (2009), Recent advances in enhancing the sensitivity of electrophoresis and electrochromatography in capillaries and microchips (2006–2008). ELECTROPHORESIS, 30: 230–248. doi: 10.1002/elps.200800435

Author Information

  1. Australian Centre for Research on Separation Science, School of Chemistry, University of Tasmania, Hobart, Tasmania, Australia

*Australian Centre for Research on Separation Science, School of Chemistry, University of Tasmania, GPO Box 252-75, Hobart, Tasmania 7001, Australia Fax: +61-3-6226-2858

Publication History

  1. Issue published online: 20 JAN 2009
  2. Article first published online: 20 JAN 2009
  3. Manuscript Revised: 18 AUG 2008
  4. Manuscript Accepted: 18 AUG 2008
  5. Manuscript Received: 4 JUL 2008

Funded by

  • Australian Research Council for funding. Grant Number: DP0666121
  • Australian Postdoctoral Fellowship. Grant Number: DP0557083
  • Egyptian ministry of higher education

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Keywords:

  • Extraction;
  • Focusing;
  • Preconcentration;
  • Stacking;
  • Sweeping

Abstract

Poor sensitivity is still considered to be one of the major limitations of electrophoresis, which is surprising given the power, flexibility and versatility of many of the approaches to on-line concentration that have developed over the last 20 years. This is still a very active area of interest and this review will cover developments in the field over the last two years since the last review (Electrophoresis 2007, 28, 254–281) through to June 2008. It includes developments in the fields of stacking, covering all methods from field-amplified sample stacking and large volume sample stacking, through to ITP, dynamic pH junction and sweeping. Attention is also given to on-line or in-line extraction methods that have been used for electrophoresis.

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