Issue no. 2 is a regular issue consisting of 18 contributions distributed over 5 distinct parts. The issue has an “Emphasis on Proteins and Proteomics” with 7 contributions featured in Part I. This is followed by Part II that has 4 research articles on nanopore and nanoparticles based analyses. Part III has 2 contributions on agarose gel electrophoresis for the analysis of the structure fluidity of a phage T3 DNA packaging intermediate and analyzing RNA quality. Part IV has two research articles on microchip capillary electrophoresis with poly(ethylene glycol)-coated microfluidic devices and poly(dimethylsiloxane) microchips using a mixture of ionic and zwitterionic surfactants. The last part (Part V) consists of 3 contributions on CE of some common controlled stimulants, CE test of a blood-brain barrier model and the simultaneous determinations of nitrite and nitrate in human plasma by CE. This issue is populated by a collection of very important research articles. It is a must read.

Featured articles include:

The challenge to quantify proteins with charge trains due to isoforms or conformers ((10.1002/elps.201100321))

Electrophoretically-driven SDS removal and protein fractionation in the shotgun analysis of membrane proteomes ((10.1002/elps.201100364))

Modeling and simulation of nanoparticle separation through a solid state nanopore ((10.1002/elps.201100201))

A novel open-tubular capillary electrochromatography with magnetic nanoparticle coating as stationary phase ((10.1002/elps.201100337))

Direct visualization of electrophoretic mobility shift assays using nanoparticle-aptamer conjugates ((10.1002/elps.201100308))