Research Article

Transplacentally exposed human and monkey newborn infants show similar evidence of nucleoside reverse transcriptase inhibitor-induced mitochondrial toxicity†

  1. Rao L. Divi1,
  2. Sarah L. Leonard1,
  3. Maryanne M. Kuo1,
  4. Kunio Nagashima2,
  5. Chandrasekhar Thamire3,
  6. Marisa C. St. Claire4,
  7. Nancy A. Wade5,
  8. Vernon E. Walker6,
  9. Miriam C. Poirier1,*

Article first published online: 14 MAR 2006

DOI: 10.1002/em.20201

Issue

Environmental and Molecular Mutagenesis

Environmental and Molecular Mutagenesis

Volume 48, Issue 3-4, pages 201–209, April - May 2007

Additional Information

How to Cite

Divi, R. L., Leonard, S. L., Kuo, M. M., Nagashima, K., Thamire, C., St. Claire, M. C., Wade, N. A., Walker, V. E. and Poirier, M. C. (2007), Transplacentally exposed human and monkey newborn infants show similar evidence of nucleoside reverse transcriptase inhibitor-induced mitochondrial toxicity. Environ. Mol. Mutagen., 48: 201–209. doi: 10.1002/em.20201

Author Information

  1. 1

    Center for Cancer Research, National Cancer Institute, NIH, Bethesda, MD

  2. 2

    NCI-Frederick, SAIC, Frederick, MD

  3. 3

    Department of Mechanical Engineering, University of Maryland,College Park, MD

  4. 4

    Bioqual Incorporated, Rockville, MD

  5. 5

    Albany Medical Center, Albany, NY

  6. 6

    Lovelace Respiratory Research Institute, Albuquerque, NM

*Carcinogen-DNA Interactions Section, National Cancer Institute, Bldg. 37, Room 4032, NIH, 37 Convent Drive, MSC-4255, Bethesda, MD 20892-4255, USA

  1. †

    Invited article on the genotoxicity of perinatal NRTI therapy.

Publication History

  1. Issue published online: 19 MAR 2007
  2. Article first published online: 14 MAR 2006

Funded by

  • National Heart Lung and Blood Institute, NIH. Grant Numbers: R01, HLO 72727
  • National Cancer Institute
  • Center for Cancer Research

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