Research Article

Genotoxicity assessed by the comet and GPA assays following in vitro exposure of human lymphoblastoid cells (H9) or perinatal exposure of mother–child pairs to AZT or AZT-3TC†

  1. Patricia A. Escobar1,
  2. Ofelia A. Olivero2,
  3. Nancy A. Wade3,
  4. Elaine J. Abrams4,
  5. Carol J. Nesel5,
  6. Roberta B. Ness6,
  7. Richard D. Day7,
  8. Billy W. Day1,
  9. Quanxin Meng8,9,
  10. J. Patrick O'Neill10,
  11. Dale M. Walker8,9,
  12. Miriam C. Poirier2,
  13. Vernon E. Walker8,9,*,
  14. William L. Bigbee1,6

Article first published online: 14 MAR 2007

DOI: 10.1002/em.20285

Issue

Environmental and Molecular Mutagenesis

Environmental and Molecular Mutagenesis

Volume 48, Issue 3-4, pages 330–343, April - May 2007

Additional Information

How to Cite

Escobar, P. A., Olivero, O. A., Wade, N. A., Abrams, E. J., Nesel, C. J., Ness, R. B., Day, R. D., Day, B. W., Meng, Q., O'Neill, J. P., Walker, D. M., Poirier, M. C., Walker, V. E. and Bigbee, W. L. (2007), Genotoxicity assessed by the comet and GPA assays following in vitro exposure of human lymphoblastoid cells (H9) or perinatal exposure of mother–child pairs to AZT or AZT-3TC. Environ. Mol. Mutagen., 48: 330–343. doi: 10.1002/em.20285

Author Information

  1. 1

    Department of Environmental and Occupational Health, University of Pittsburgh, Pittsburgh, Pennsylvania

  2. 2

    Carcinogen-DNA Interactions Section, National Cancer Institute, NIH, Bethesda, Maryland

  3. 3

    Department of Pediatrics, Children's Hospital at Albany Medical Center, Albany, New York

  4. 4

    Department of Pediatrics, Columbia University College of Physicians and Surgeons and Harlem Hospital Center, New York, New York

  5. 5

    Westat, Inc., Rockville, Maryland

  6. 6

    Department of Epidemiology, University of Pittsburgh, Pittsburgh, Pennsylvania

  7. 7

    Department of Biostatistics, University of Pittsburgh, Pittsburgh, Pennsylvania

  8. 8

    Wadsworth Center, New York State Department of Health, Albany, New York

  9. 9

    Lovelace Respiratory Research Institute, Albuquerque, New Mexico

  10. 10

    Genetics Laboratory, University of Vermont, Burlington, Vermont

*Lovelace Respiratory Research Institute, 2425 Ridgecrest Drive SE, Albuquerque, NM 87108

  1. †

    Invited article on the genotoxicity of perinatal NRTI therapy.

Publication History

  1. Issue published online: 19 MAR 2007
  2. Article first published online: 14 MAR 2007

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