Proper synaptic vesicle formation and neuronal network activity critically rely on syndapin I (pages 4955–4969)
Dennis Koch, Isabella Spiwoks-Becker, Victor Sabanov, Anne Sinning, Tamar Dugladze, Anne Stellmacher, Rashmi Ahuja, Julia Grimm, Susann Schüler, Anke Müller, Frank Angenstein, Tariq Ahmed, Alexander Diesler, Markus Moser, Susanne tom Dieck, Rainer Spessert, Tobias Maria Boeckers, Reinhard Fässler, Christian Andreas Hübner, Detlef Balschun, Tengis Gloveli, Michael Manfred Kessels and Britta Qualmann
Version of Record online: 16 SEP 2011 | DOI: 10.1038/emboj.2011.339
F-BAR domain proteins sense or induce membrane curvature and play a widespread role in intracellular trafficking events. This study characterizes syndapin I knockout mice at the neurological, cell biological and molecular levels and demonstrates that this F-BAR protein acts as membrane anchoring factor for dynamins during synaptic vesicle regeneration.